A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates
Kwantae Kim,
Katarzyna M. Piekarz,
Alberto Stolfi
Abstract:Transcriptional regulation of gene expression is an indispensable process in multicellular development, yet we still do not fully understand how the complex networks of transcription factors operating in neuronal precursors coordinately control the expression of effector genes that shape morphogenesis and terminal differentiation. Here we break down in greater detail a provisional regulatory circuit downstream of the transcription factor Pax3/7 operating in the descending decussating neurons (ddNs) of the tuni… Show more
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