A gallium telluride quantum dots bioelectrode system for human epidermal growth factor receptor-2 (Her2/neu) oncogene signalling

Fuku, Xolile; Singh, Balwinder; Ajayi, Rachel Fanelwa; Jijana, Abongile Nwabisa; Baker, Priscilla; Dempsey, Eithne; Iwuoha, Emmanuel I.

doi:10.1039/c5ay00962f

Cited by 10 publications

(7 citation statements)

References 54 publications

(108 reference statements)

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“…Notably, at 600 °C the TGA curves reveal no weight loss of the nanocatalyst, thus concluding a thermally stable and pure Cu/Cu 2 O/CuO nanocomposite. The results are in agreement with our previous FTIR results [38]. The results further confirm that the thermal decomposition of the catalyst is complete below 600 °C.…”

Section: Crystallinity Of Cu/cu 2 O/cuo Npssupporting

confidence: 93%

“…8 g of the copper chloride salt was then dissolved in 200 mL of pomegranate broth and the aliquot was subjected to a constant temperature (80 °C), after which a dark green-brown precipitate of copper/ cupric oxide (Cu/Cu 2 O/CuO) nanoparticles (NPs) (pH 5) was formed. For microscopic (SEM) and spectroscopic (XRD) analysis, the precipitate was collected via centrifugation (10 min, 1000 rpm) and the nanomaterials washed with deionized H 2 O three times in order to remove loosely bound materilas, using a centrifuge and a sonicator [38]. 80% yield of the nanopowder was realised and was oven dried at 65 °C, 30 min.…”

Section: Synthesis Of Reduced Cu/cu 2 O/cuo Nanoparticles From Pomegrmentioning

confidence: 99%

“…The electrode was labelled as GC/Cu/Cu 2 O/CuO. For electrochemical measurements Phosphate buffer solution (0.1 M, pH 7) was employed as the electrolyte as was noted from previous our study [38] (Scheme 1). Figure 1a shows the UV-visible absorption spectra of colloidal Cu/Cu 2 O/CuO nanoparticles with average nanoparticle sizes of 5-20 nm.…”

Section: Preparation Of Gc/cu/cu 2 O/cuo Electrodesmentioning

confidence: 99%

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Green synthesis of Cu/Cu2O/CuO nanostructures and the analysis of their electrochemical properties

Fuku¹,

Modibedi²,

Mathe³

2020

SN Appl. Sci.

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Heterogeneous Cu/Cu 2 O/CuO nanoparticles were synthesised via polyphenols of pomegranate for various application. X-ray diffraction and high resolution-scanning electron microscopy confirmed Cu/Cu 2 O/CuO NPs crystallinity and the particle size which ranged from 5 to 20 nm. The electrochemical band gap energies of Cu/Cu 2 O/CuO NPs were calculated to be between 0.9 and 2.1 eV. EIS measurements were used to calculate the capacitance and specific capacitance of the nanoparticles which were found to be 11.2 F and 69 F g −1 . Surface diffusion coefficient obtained from cyclic voltammetry was found to be 1.54 × 10 −6 cm 2 s −1 with r 2 of 0.99 suggesting a fast electron movement. The calculated surface coverage was 1.38 × 10 −3 mol cm −2 suggesting the formation of monolayer at the electrode interface. The results confirmed the electroactivity of Cu/Cu 2 O/CuO electrode towards the volatile organic compound-ethanol. Cu/Cu 2 O/CuO exhibited good electrochemical performance towards ethanol with higher current density and most negative onset potential − 0.3 V, meaning that it requires lower energy for ethanol activity to occur at the electrode interface. EIS profiles confirmed the kinetics of Cu/Cu 2 O/CuO at the electrode surface with characteristic small circular curvature signifying that the polarisation resistance (R p ) is prominent, proposing a faster electron shuttling process for ethanol activity. Further, the amperometric response with long time test for the Cu/Cu 2 O/CuO based electrode system estimated a lower limit of detection to be 0.09 µM at a signal to noise ratio of 3 with sensitivity of 0.049 µA µM −1 at steady state. Raman and FTIR highlighted mechanism of coordination.

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Section: Crystallinity Of Cu/cu 2 O/cuo Npssupporting

confidence: 93%

Section: Synthesis Of Reduced Cu/cu 2 O/cuo Nanoparticles From Pomegrmentioning

confidence: 99%

Section: Preparation Of Gc/cu/cu 2 O/cuo Electrodesmentioning

confidence: 99%

See 1 more Smart Citation

Green synthesis of Cu/Cu2O/CuO nanostructures and the analysis of their electrochemical properties

Fuku¹,

Modibedi²,

Mathe³

2020

SN Appl. Sci.

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“…The emission is known to be caused by the radiative recombination of a photogenerated hole with an electron occupying the oxygen vacancy [28,40]. From the 509 nm emission peak the band gap energy of the nanosized ZnO was calculated using Planck's equation and was found to be 3.4 eV, which is comparable with that observed in UV-vis and literature [35,[37][38][39]41]…”

Section: Formation and Structural Characterisation Of Znosupporting

confidence: 67%

“…In the XRD patterns, the (101) plane corresponding to 36.8 ∘ was found to be very clear and abundant which indicates preferential growth of the crystallites. The average size was calculated using the Scherrer equation [16,32,34,37]…”

Section: Formation and Structural Characterisation Of Znomentioning

confidence: 99%

Nanoscaled Electrocatalytic Optically Modulated ZnO Nanoparticles through Green Process ofPunica granatumL. and Their Antibacterial Activities

Fuku

Diallo

Mâaza

2016

International Journal of Electrochemistry

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Most recently, green synthesis of metal oxide nanoparticles has become an interesting subject of the nanoscience and nanotechnology. The use of plant systems has been deemed a green route and a dependable method for nanoparticle biosynthesis, owing to its environmental friendly nature. The present work demonstrates the bioreductive green synthesis of nanosized zinc oxide (ZnO) using peel extracts of pomegranate. Highly crystalline ZnO nanoparticles (ZnO NPs) which are 5 nm in particle size were characterised by HRTEM and XRD. FT-IR spectra confirmed the presence of the biomolecules and formation of plant protein-coated ZnO NPs and also the pure ZnO NPs. Electrochemical investigation revealed the redox properties and the conductivity of the as-prepared ZnO nanoparticles. The optical band gap of ZnO NPs was calculated to be 3.48 eV which indicates that ZnO NPs can be used in metal oxide semiconductor-based devices. Further, the nanomaterials were also found to be good inhibitors of bacterial strains at both low and high concentrations of 5–10 mg mL−1.

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Influence of Quantum Dot Surface on Electrochemical DNA Sensing Mechanism

2020

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Owing to their high surface‐to‐volume ratio, electrocatalytic activity, biocompatibility and novel electron transport properties, quantum dots (QDs) are highly attractive materials for the ultrasensitive detection of biological macromolecules via bioelectronic devices. In this study, a QD‐based genosensor was developed, in which Ga2Te3‐based QDs were synthesized using an aqueous solution approach by mixing 3‐mercaptosuccinic acid (3MSA)‐capped gallium metal precursor with reduced tellurium metal. The results enabled us to reach an original understanding related to the active material involved in the probe DNA sensing mechanism. The morphological and structural characterization of the QDs was performed prior to their utilization in a DNA sensor construction. High‐resolution TEM (HR‐TEM) and atomic force microscopy (AFM) images confirmed the spherical and crystalline nature of the QDs, whereas X‐ray photoelectron spectroscopy (XPS) and X‐ray diffraction (XRD) analyses were able to confirm the oxidation states and formation of the prepared QDs. UV/Vis was capable of finding the optical band gap energy and the photostability of the QDs. The resultant Ga2Te3 QDs together with metal ions confirmed their use for DNA signal detection through their DNA binding mechanism in the genosensor construction. Genosensing in Cs+ and Li+ ions exhibited high sensitivity (2.74–3.69 μA ng−1 mL) and very low detection limits (0.4 pg mL−1) with a linear dynamic range of 0.1–1 ng mL−1.

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A gallium telluride quantum dots bioelectrode system for human epidermal growth factor receptor-2 (Her2/neu) oncogene signalling

Cited by 10 publications

References 54 publications

Green synthesis of Cu/Cu2O/CuO nanostructures and the analysis of their electrochemical properties

Green synthesis of Cu/Cu2O/CuO nanostructures and the analysis of their electrochemical properties

Nanoscaled Electrocatalytic Optically Modulated ZnO Nanoparticles through Green Process ofPunica granatumL. and Their Antibacterial Activities

Influence of Quantum Dot Surface on Electrochemical DNA Sensing Mechanism

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