We were interested to r ead the pa per by Di Somma et al. (Nasal dil ator strips increase maximum in spiratory flow via nasal wall stabi lization. Laryngoscope 1999;109: 780 -784) that claims to show tha t external nasal dilator strips (ENDS) increase peak nasal airflow by stabilizing the lat ral wall of th nose. However, there are several fe tures of this pa per that should not pass without comment.It is critical in all s uch experimental studies to try to eliminat expectation and performance bias in both the subject a nd th e inv stigator. In this paper nasal decongestion did not incr ase peak inspiratory flow, but th.is is contrary to our exp rience and that of others who have found th t both inspiratory and expiratory flow are markedly incr ased when mucosa! resistance is reduced.
1~Moreover , the a uthors found that using ENDS in the d congest d nose further incr ases peak expiratory flow . But splinting of th lateral nasal wall, however it is done, cannot account for this physiologically and it would seem mor likely that the subj ects were subconsciously increasing th ir effort to maximize their peak flow once a dilator strip was appli d. We have found that nasal spirometry produc s variable results, with peak nasal inspiratory flow measurem nts in the decongested nose having a coefficient of variation of 15.05%.' 1 It is clear that any add itional bi as, specially in a small sample, may easily appea r to show significance wh re none exists. It is our custom to standardize spirometry r eadings, in an attempt to reduc errors, by taking the best of at least three recordings-as is done in pulmonary measurement. Even doing thi s is probably in sufficient, but the authors appear to h ave simply allowed a variable number of practice attempts followed by on e r ading, which they have r cord d.The discussion appears to confuse alar collapse with stabili za tion of th e lateral wall at the level of the nasal valv . It is widely accepted that the nasal valve is formed at the isthmus of the nose and is the area where the upper lateral cartilage unites with th dorsal septum. Although lateral wa ll movem ent occurs with maximal respiratory effort, particularly at the caudal end of the upper lateral cartilage, in tho healthy nose it is the mucosa! reactivity of th e head of the inferior turbina te that produces the majority of the valvul a r action at this site. 2 By contrast , we b li v that alar flarin g on inspiration is both passive (Bernoulli's principl ) and active (the dilator nar s muscl e). Flaring appears to act to stent the upper lateral cartilag through the intercartilaginous ligaments and will help to stabilize the later l wall of the nose at the Laryngoscope 110: January 2000 178 level of the valve. However, it is not influenced by the application of an external splint. 2 Finally, in what we assume was an effort to make the differences obtained look more meaningful than they were, the authors have shown means and standard errors of the means for their data when they should have listed the means and stand a...