A Function of the Eosinophil: Phagocytosis of Antigen-ntibody Complexes.

Sabesin, Seymour M.

doi:10.3181/00379727-112-28134

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Other Lymphocyte-eosinophil Interactive Mechanisms1

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Cited by 96 publications

(24 citation statements)

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“…Eosinophils are known to infiltrate collections of mast cells [16] and to be attracted by antigen-antibody complexes [20]. Histamine [2] is chemotactic for eosinophils, and by analogy we infer that this explanation is rational in this case.…”

Section: Discussionmentioning

confidence: 79%

Generalized Equine Cutaneous Mastocytosis

et al. 1972

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Abstract.A newborn foal developed generalized cutaneous mastocytosis characterized by multiple elevated nodules of mast cells in skin and basophil hyperplasia in bone marrow. Skin lesions began as small aggregates of mast cells that progressively enlarged, ulcerated, and regressed spontaneously. Eosinophil infiltration, collagen necrosis, and fibroplasia were characteristic of advanced lesions. Many new lesions developed during the first month of life but numbers progressively diminished.

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Section: Discussionmentioning

confidence: 79%

Generalized Equine Cutaneous Mastocytosis

et al. 1972

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“…In mucosal sites, eosinophils will be present with antibodies of all three classes; and for inhaled allergens, IgG, IgE and IgA antibodies to relevant antigens are measurable in mucosal secretions (Platts-Mills 1979, Kitani et al 1985, Desvaux et al 1989. Interestingly, older studies of eosinophils had demonstrated that eosinophils were very effective in the uptake of antigen-antibody complexes (Sabesin 1963, Litt 1964a.…”

Section: Other Lymphocyte-eosinophil Interactive Mechanismsmentioning

confidence: 99%

Human eosinophil-lymphocyte interactions

Weller

Lim

1997

Mem. Inst. Oswaldo Cruz

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“…There is much evidence that antigen-antibody complexes are eosinotactic and are phagocytosed by eosinophils [20,25,33,34,35,36]. Thus, the main function of eosinophils is probably related to the formation or disposal of antigen-antibody complexes.…”

Section: Discussionmentioning

confidence: 99%