“…1,26,28 Any component of the system can contribute to the whole systematic error; problems may arise from image distortion, target displacement due to tissue deformation or unexpected movement, registration error, optical localizer error, the limitations of the control and compensation algorithm, inherent kinematic limitation, needle deflection, and human error. 18,22,28 Although it is difficult to separate the contribution of each component, needle deflection is primarily responsible for needle displacement in previous studies. 2,19,23,24 The option of correcting needle deflection is to create a model for theoretically estimating needle-tissue interaction so that compensation can be made in advance (during planning).…”