A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions

Superbase-Mediated gem-Difluoroalkenylations of Sulfoximines

“…Sulfoximines have been identified as relevant for medicinal and crop protection chemistry . As in other molecules, fluoro substituents significantly affect the properties of sulfoximines . While most fluorinated sulfoximines are rather stable, some rapidly react by selective S–C bond cleavage, allowing for their use, for example, as highly effective electrophilic fluoroalkylating agents .…”

Catalyst-free electrochemical trifluoromethylation of coumarins using CF3SO2NHNHBoc as the CF3 source

“…14 Trifluoromethylated compounds have widespread applications in the pharmaceutical and agrochemical industries, and as functional materials. [15][16][17] Meanwhile, novel trifluoromethylation reagents and creative trifluoromethylation methods 18,19 have also been extensively developed. In this context, the introduction of the trifluoromethyl group into coumarins is of great interest for both organic and medicinal communities.…”

Transfer of an Aluminium Atom: An Avenue to Aluminium Heterocycles

“…Synthetic chemistry not only aims to construct molecular complexity from simple feedstocks, but also to exert selective modifications to chemically complex molecules. [1][2][3][4] Single-atom transfer reactions that perform atomically precise additions of molecular architectures are one of the ideal approaches (Figure 1a). 5 Indeed, precise delivery of a chalcogen atom to a low valent main group center has opened avenues to unique species.…”