A “freeze-all” embryo strategy after in vitro maturation: a novel approach in women with polycystic ovary syndrome?

Ortega-Hrepich, Carolina; Stoop, Dominic; Guzmán, Luis; Landuyt, Lisbet Van; Tournaye, Herman; Smitz, Johan; Vos, Michel De

doi:10.1016/j.fertnstert.2013.06.018

Cited by 53 publications

(32 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the context of modern milder approaches to ART and the increasing demand from patients for a simpler, cheaper, more patient-friendly reproductive technology, the search for improvements in IVM are continuing and improved pregnancy rates have recently been established by a number of centres (Junk & Yeap 2012, Ortega-Hrepich et al 2013, Walls et al 2015a. Nonetheless, the reduced pregnancy rates per cycle compared with conventional IVF represents a major obstacle that needs to be overcome for widespread uptake of IVM.…”

Section: Cyclic Nucleotides and Oocyte Quality In Vitro Maturation (Ivm)mentioning

confidence: 99%

Oocyte maturation and quality: role of cyclic nucleotides

Gilchrist¹,

Luciano²,

Richani³

et al. 2016

Reproduction

166

109

View full text Add to dashboard Cite

The cyclic nucleotides, cAMP and cGMP, are the key molecules controlling mammalian oocyte meiosis. Their roles in oocyte biology have been at the forefront of oocyte research for decades, and many of the long-standing controversies in relation to the regulation of oocyte meiotic maturation are now resolved. It is now clear that the follicle prevents meiotic resumption through the actions of natriuretic peptides and cGMP -inhibiting the hydrolysis of intra-oocyte cAMP -and that the pre-ovulatory gonadotrophin surge reverses these processes.

show abstract

Section: Cyclic Nucleotides and Oocyte Quality In Vitro Maturation (Ivm)mentioning

confidence: 99%

Oocyte maturation and quality: role of cyclic nucleotides

Gilchrist¹,

Luciano²,

Richani³

et al. 2016

Reproduction

166

109

View full text Add to dashboard Cite

show abstract

“…Este resultado fue confirmado por OrtegaHrepich y cols al publicar los resultados clínicos en pacientes con SOP en quienes se transfirieron embriones derivados de ciclos de MIV sin hCG, los cuales fueron todos vitrificados y transferidos en ciclos posteriores (22), reportando una tasa de embarazo clínico y de recién nacido vivo de 35,9% y 21,8% respectivamente.…”

Section: Discussionunclassified

Maduración in vitro de ovocitos humanos: una opción para preservar la fertilidad de las mujeres. Reporte del primer caso realizado en Chile

Ortega-Hrepich¹,

M²,

Arguello³

et al. 2014

Rev. chil. obstet. ginecol.

Self Cite

View full text Add to dashboard Cite

“…However, endometrial development may be insufficient compared with that of natural or stimulated cycles. In this regard, a recent study showed that embryos generated from IVM can be successfully cryopreserved and transferred during the next hormone replacement cycle with high implantation and pregnancy rates [26]. Furthermore, the underlying health conditions in IVM candidates may contribute to low implantation and pregnancy rates following the procedure.…”

Section: Implantation Environmentmentioning

confidence: 99%

In vitromaturation of human oocytes: Its role in infertility treatment and new possibilities

Chang

Song

Lee

et al. 2014

Clin Exp Reprod Med

View full text Add to dashboard Cite

IVM refers to the maturation of immature oocytes in culture after their recovery from small antral follicles at the stage prior to selection and dominance. IVM requires little or no FSH in vivo and has been proposed as an alternative to conventional IVF, since it reduces the primary adverse effects caused by controlled ovarian stimulation, including the ovarian hyperstimulation syndrome. Moreover, IVM is a promising option for cases for which no standard protocol is suitable, such as FSH resistance, contraindications for ovarian stimulatory drugs, and the need for urgent fertility preservation. Recently, IVM has been used in women with regular cycles and normal ovaries. However, the pregnancy rate following IVM is suboptimal compared with that of conventional IVF, indicating that further studies to optimize the protocol and the culture conditions are warranted.

show abstract

A “freeze-all” embryo strategy after in vitro maturation: a novel approach in women with polycystic ovary syndrome?

Cited by 53 publications

References 35 publications

Oocyte maturation and quality: role of cyclic nucleotides

Oocyte maturation and quality: role of cyclic nucleotides

Maduración in vitro de ovocitos humanos: una opción para preservar la fertilidad de las mujeres. Reporte del primer caso realizado en Chile

In vitromaturation of human oocytes: Its role in infertility treatment and new possibilities

Contact Info

Product

Resources

About