A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation

Abstract

SUMMARYThis paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.

Artificial Intelligence: A New Paradigm for Pharmaceutical Applications in Formulations Development

“…The operation knowledge is a procedural knowledge which is described in production rule. 13 In 2013, Nopphadol Chalortham et al used the OXPIRT for the production of immediate-release tablets. This tool provides a better path for a pharmacist to produce a generic immediate-release tablet in a laboratory-scale production.…”

Ontology Based Framework for Interactive Self-Assessment of e-Health Applications

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