2009
DOI: 10.1111/j.1365-4632.2008.04035.x
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A fraction of deep vascular birthmarks are true deep hemangiomas of infancy

Abstract: It was demonstrated that all deeply-located vascular birthmarks are not true deep HOIs. It is recommended that diagnosis for HOI be carried out cautiously earlier in life using GLUT1 in addition to clinical features. This would help prevent patients from being misled by anticipating the spontaneous involution in all deeply-located vascular birthmarks.

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Cited by 6 publications
(7 citation statements)
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“…Patients may present with complaints of pain and swelling and this is usually related to clot formation either from trauma or venous stasis (Mavrikakis et al , 2009). Frequently, patients will have their malformations misdiagnosed as hemangiomas (MacFie and Jeffery, 2008; Bruder et al , 2009; Lee et al , 2009b). This misdiagnosis not only delays treatment because they are told the lesions will regress, but it can result in inappropriate therapy such as interferon, which can have devastating irreversible side‐effects.…”
mentioning
confidence: 99%
“…Patients may present with complaints of pain and swelling and this is usually related to clot formation either from trauma or venous stasis (Mavrikakis et al , 2009). Frequently, patients will have their malformations misdiagnosed as hemangiomas (MacFie and Jeffery, 2008; Bruder et al , 2009; Lee et al , 2009b). This misdiagnosis not only delays treatment because they are told the lesions will regress, but it can result in inappropriate therapy such as interferon, which can have devastating irreversible side‐effects.…”
mentioning
confidence: 99%
“…Dynamic observation is very important; as shown in case 2, in which US revealed small‐bowel wall segmental thickening only when the intestine was contracted. GI venous malformations are characterized by uniform thickening of the intestinal wall and compressible masses that do not cause stenosis of the intestinal cavity because they include abnormal vessels and show cellular turnover without proliferation or cellular hyperplasia 11,12 …”
Section: Discussionmentioning
confidence: 99%
“…While certain types such as deep IHs may not be easily distinguished from other vascular anomalies without radiologic or histopathologic assistance, those of superficial or mixed type may be clinically diagnosed 8 . Typically, IHs are absent at birth 9 .…”
Section: Introductionmentioning
confidence: 99%