A force plate system for measuring low-magnitude reaction forces in small laboratory animals

Handley, D.; Ross, Joseph F.; Carr, Gregory J.

doi:10.1016/s0031-9384(98)00108-5

Cited by 9 publications

(4 citation statements)

References 28 publications

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“…One problem that can arise with the use of force plates to examine the gait of small rodents is the production of vibrational noise as each limb impacts the surface. Various techniques are used to reduce this (Handley, Ross, & Carr, 1998). Such interference, however, is not a problem in our load-cell-based system.…”

Section: Methodsmentioning

confidence: 99%

Ground reaction force and spatiotemporal measurements of the gait of the mouse

Clarke

Smart

Still

2001

Behavior Research Methods, Instruments, & Computers

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Measurement of ground reaction forces with force plates permits quantification of the subtle changes in movement associated with a variety of pathophysiological states. The apparatus used here permits simultaneous recording of other spatial and temporal characteristics of gait. Since the mouse is becoming increasingly important for modeling human disorders, we have recorded ground reaction forces (P) in this species. To date, we have measured the vertical component (Pz) and found it to be similar to that of other species, in that a greater Pz is exerted via the forelimb, although the areas under the force/time curves, are not different. Different points of discontinuity are seen in the forelimb and hindlimb curves, indicating differential deployment. Pz varies consistently with stance time and is consistent across the adult life of the mouse. It is suggested that the technique has potential for the study of a variety of mouse models of disease and of their therapies.

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Section: Methodsmentioning

confidence: 99%

Ground reaction force and spatiotemporal measurements of the gait of the mouse

Clarke

Smart

Still

2001

Behavior Research Methods, Instruments, & Computers

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“…Kinetic data for small animals are traditionally collected using small handbuilt force plates (Heglund, 1981;Full and Tu, 1991;Biewener and Full, 1992;Ahn et al, 2004) that are difficult to build and can be fragile. Clarke and colleagues (Rochester and Clarke, 1994;Clarke and Still, 1999; and Handley et al (1998) have provided important and valuable data on rodent vertical ground reaction forces. However, their equipment is not commercially available and does not provide information about the anteroposterior or mediolateral reaction forces.…”

Section: Introductionmentioning

confidence: 99%

Force plate for measuring the ground reaction forces in small animal locomotion

Zumwalt

Hamrick

Schmitt

2006

Journal of Biomechanics

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“…The force necessary to stimulate a forelimb‐placing reaction or the strength of reflex withdrawal and hopping responses can be compared between spinal‐injured and control animals (Kunkel et al . 1993; Handley et al . 1998; Bennett et al .…”

Section: Kinetic Measuresmentioning

confidence: 99%

Assessment of behavioural recovery following spinal cord injury in rats

Muir

Webb

2000

Eur J of Neuroscience

105

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Behavioural recovery is one of the primary goals of therapeutic intervention in animal models of disease. It is necessary, therefore, to have the means with which to quantify pertinent behavioural changes in experimental animals. Nevertheless, the number and diversity of behavioural measures which have been used to assess recovery after experimental interventions often makes it difficult to compare results between studies. The present review attempts to integrate and categorize the wide variety of behavioural assessments used to measure recovery in spinal-injured rats. These categories include endpoint measures, kinematic measures, kinetic measurements, and electrophysiological measurements. Within this categorization, we discuss the advantages and disadvantages of each type of measurement. Finally, we make some recommendations regarding the principles for a comprehensive behavioural analysis after experimental spinal cord injury in rats.

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A force plate system for measuring low-magnitude reaction forces in small laboratory animals

Cited by 9 publications

References 28 publications

Ground reaction force and spatiotemporal measurements of the gait of the mouse

Ground reaction force and spatiotemporal measurements of the gait of the mouse

Force plate for measuring the ground reaction forces in small animal locomotion

Assessment of behavioural recovery following spinal cord injury in rats

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