A follow-up study of peri-implantitis cases after treatment

The aim of the present randomized controlled clinical trial was to investigate the adjunctive effect of systemic antibiotics and the local use of chlorhexidine for implant surface decontamination in the surgical treatment of peri-implantitis. One hundred patients with severe peri-implantitis were recruited. Surgical therapy was performed with or without adjunctive systemic antibiotics or the local use of chlorhexidine for implant surface decontamination. Treatment outcomes were evaluated at 1 y. A binary logistic regression analysis was used to identify factors influencing the probability of treatment success, that is, probing pocket depth ≤5 mm, absence of bleeding/suppuration on probing, and no additional bone loss. Treatment success was obtained in 45% of all implants but was higher in implants with a nonmodified surface (79%) than those with a modified surface (34%). The local use of chlorhexidine had no overall effect on treatment outcomes. While adjunctive systemic antibiotics had no impact on treatment success at implants with a nonmodified surface, a positive effect on treatment success was observed at implants with a modified surface. The likelihood for treatment success using adjunctive systemic antibiotics in patients with implants with a modified surface, however, was low. As the effect of adjunctive systemic antibiotics depended on implant surface characteristics, recommendations for their use in the surgical treatment of peri-implantitis should be based on careful assessments of the targeted implant (ClinicalTrials.gov NCT01857804).

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“…For details regarding checkerboard DNA-DNA hybridization and culture techniques, see the Appendix and Charalampakis et al (2011).…”

Section: Microbiological Sampling and Analysismentioning

confidence: 99%

Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis

et al. 2015

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“…It is not clear if the microbial composition of a biofilm is affected by the physicochemical properties and texture characteristics of the implant surface. Higher roughness and higher free energy of the implant surface may favour biofilm formation (35), whereas peri-implantitis may occur earlier, with a faster and more extensive progression in implants with rougher surface (36)(37)(38). Nevertheless, it is also shown that abutments with different surface characteristics can influence neither biofilm formation on the implant surface, nor the extent and cellular composition of the resulting inflammatory lesion (39).…”

Section: Such As Staphylococcus Aureus Staphylococcus Epidermidis Ementioning

confidence: 99%

Microbiological and immuno-pathological aspects of peri-implant diseases

Belibasakis

2014

Archives of Oral Biology

165

135

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“…Charalampakis, et al evaluated the longevity and incidence of relapse of multiple different treatments on periimplantitis lesions. 107 Over half of the cases evaluated relapsed and were not controlled. Patient habits and early disease development were associated with higher rates of relapse and surgical therapy with lower rates of relapse.…”

Section: Discussionmentioning

confidence: 99%

“…Patient habits and early disease development were associated with higher rates of relapse and surgical therapy with lower rates of relapse. 107 Long-term success of an implant depends on regular maintenance program. During maintenance phase, peri-implant tissue should be evaluated for inflammation.…”

Section: Discussionmentioning

confidence: 99%

Peri-Implantitis: A Review of the Disease and Report of a Case Treated with Allograft to Achieve Bone Regeneration

Rashid¹,

Sheikh²,

Vohra³

et al. 2015

Dent Open J

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Dental implants offer excellent tooth replacement options however; peri-implantitis can limit their clinical success by causing failure. Peri-implantitis is an inflammatory process around dental implants resulting in bone loss in association with bleeding and suppuration. Dental plaque is at the center of its etiology, and in addition, systemic diseases, smoking, and parafunctional habits are also implicated. The pathogenic species associated with peri-implantitis include, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythia. The goal in the management of peri-implantitis is the complete resolution of peri-implant infection with function. Therapies using various biomaterials to deliver antibiotics have been used in the treatment of peri-implantitis e.g. fibers, gels, and beads. The use of guided tissue regeneration barrier membranes loaded with antimicrobials has shown success in re-osseointegrating the infected implants in animal models. Several uncertainties still remain regarding the management of peri-implantitis. The purpose of this article is to present a background of peri-implantitis along with a case of peri-implantitis successfully treated for bone regeneration.

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A follow-up study of peri-implantitis cases after treatment

Abstract: Peri-implant health may not be easy to establish, especially in cases that develop disease early. Homogenous treatment protocols rather than empirical treatment attempts should be adopted.

Cited by 85 publications

References 45 publications

Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis

Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis

Microbiological and immuno-pathological aspects of peri-implant diseases

Peri-Implantitis: A Review of the Disease and Report of a Case Treated with Allograft to Achieve Bone Regeneration

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