A Follow‐Up Study of 91 Patients Operated on for Focal Epilepsy

Bhatia, Ravi; Kollevold, T; Sánchez, Abel; Reitter, B.

doi:10.1111/j.1528-1157.1976.tb03383.x

Cited by 16 publications

(7 citation statements)

References 9 publications

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“…In series with patients followed for 6 months to 10 years, investigators should report separately the results of patients followed for different periods, e.g., 6 months and 1, 2, 5 , and 10 years. Combining results of all patients and reporting on an average follow-up time makes interpretation of the results difficult, (Falconer et al, 1963;Bhatia et al, 1976;Davidson et al, 1975;Jensen, 1975;Rasmussen, 1980;Lindsay et al, 1984;Brey et al, 1985;King et al, 1986). On the other hand, there is no single magic follow-up time.…”

Section: Discussionmentioning

confidence: 99%

Quantitative Analysis of Seizure Frequency 1 Week and 6, 12, and 24 Months After Surgery of Epilepsy

et al. 1994

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We made quantitative analysis of seizure frequency 1 week and 6, 12, and 24 months after seizure surgery. Seizure recurrence was significantly higher when seizures occurred in the first postoperative week. Seizure recurrence increased progressively with longer follow-ups, but the 6 month postoperative follow-up period was an excellent index of long-term outcome. In operative follow-up studies, seizure frequency should be reported at fixed follow-up periods, e.g., at 6 months and 1, 2, 5, and 10 years. Meaningful comparison of outcomes between different studies is possible only when reports include outcome at fixed postoperative follow-up periods (as opposed to ranges of follow-up periods).

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Section: Discussionmentioning

confidence: 99%

Quantitative Analysis of Seizure Frequency 1 Week and 6, 12, and 24 Months After Surgery of Epilepsy

et al. 1994

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“…Three other studies have shown a bivariate connection between duration of seizure disorder and PREDICTING SUCCESSFUL NEUROSURGERY 575 seizure relief (Stepien et al, 1969;Jensen, 1976;Bergen et al, 1984), whereas five studies showed no such connection (Bloom et al, 1959160;Bengzon et al, 1968;Bathia and Kollevold, 1976;Wannamaker and Matthews, 1976;Dodrill et al, 1986). We suspect that one reason why so many studies have failed to show a relation between outcome and duration of seizure disorder is that only linear relations were examined.…”

Section: Duration Of Diseasementioning

confidence: 98%

“…Patients who were unduly apprehensive or under the age of 12-15 years were operated under general anaesthesia. An attempt was made to map the area of maximum epileptogenic activity and excise it without encroaching upon areas likely to cause neurologic deficit (Bathia and Kollevold, 1976).…”

Section: Measurements and Modelmentioning

confidence: 99%

Predictive Factors for Success in Surgical Treatment for Partial Epilepsy: A Multivariate Analysis

Guldvog

Løyning²,

Hauglie-Hanssen

et al. 1994

Epilepsia

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We conducted a longitudinal self-controlled study of 131 patients aged 4-60 treated with resective surgery for medically uncontrolled partial epilepsy from 1949 to 1988. Using multivariate logistic regression, we showed that pre- and perioperative variables can be used to predict "success" or "failure" of surgical resective treatment in approximately 79% of cases. If the predicted probability is > 0.75 or < 0.25, the model predicts a correct result in 87% of cases. Eight predictive factors emerged with a backward multivariate logistic regression model with the likelihood-ratio (LR) test to exclude variables from the equation: (a) the influence of the surgical team and surgical procedure, (b) the presence of paresis preoperatively, (c) duration of disease, (d) age at treatment, (e) positive neuroradiologic findings in preoperative investigations, (f) preoperative complex partial seizures (CPS), (g) nonepileptic EEG abnormalities, and (h) generalized spike activity in EEG preoperatively. Sex, age at first seizure, area of resection, presence of simple or generalized seizures preoperatively, preoperative seizure frequency, tissue pathology, use of computed tomography/nuclear magnetic resonance (CT/NMR) in preoperative investigations, degree of preoperative neurologic deficit, perioperative electrocorticographic results, and bilateral EEG spikes did not have predictive value in the model.

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“…An attempt was made to map the area of maximum epileptogenic activity and excise it without encroaching upon areas likely to cause neurologic deficit (Bathia and Kollevold, 1976).…”

Section: Surgical Treatment For Partial Epilepsy Amongmentioning

confidence: 99%

“…At Oslo City Hospital, most procedures were tailored resections (average basolateral length of resection in a sample of 22 patients was 5.6 cm) (Bathia and Kollevold, 1976):…”

Section: Surgical Treatment For Partial Epilepsy Amongmentioning

confidence: 99%

Surgical Treatment for Partial Epilepsy Among Norwegian Adults

Guldvog¹,

Løyning²,

Hauglie-Hanssen

et al. 1994

Epilepsia

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We conducted a retrospective longitudinal self-controlled study of 124 adult patients treated with resective surgery for medically uncontrolled partial epilepsy from 1949 to 1988. Approximately 65% of the patients experienced > 95% reduction in seizure frequency, and 75% had worthwhile improvement of at least 75% seizure reduction. Significant reductions were noted in all major seizure types treatable with resective surgery; complex partial (CPS), simple partial (SPS), and secondarily generalized tonic-clonic seizures (GTC) (all p < 0.05). Tissue pathology and region of resection did not provide significant information with respect to seizure outcome. EEG in the first postoperative year was an important predictor of long-term seizure outcome (p = 0.03). One third of the temporal lobe resected patients had neurologic deficits as a consequence of the resection as compared with 14% of patients with frontal resections (p = 0.03). One third of the deficits among the temporal lobe resected patients were considerable, with possible social implications. Half of the patients with preoperative focal spike activity had a normal EEG postoperatively. One fifth of patients maintained their preoperative epileptic focus after the operation, and about one fifth displayed new foci. Approximately one fourth of the patients were free of medication for a median of 16 years postoperatively, and 60% of patients who were seizure-free were still receiving medication. There was no operative mortality, but the late mortality, as expected, was higher than that of the general population. Two male patients (1.6%) committed suicide.

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A Follow‐Up Study of 91 Patients Operated on for Focal Epilepsy

Cited by 16 publications

References 9 publications

Quantitative Analysis of Seizure Frequency 1 Week and 6, 12, and 24 Months After Surgery of Epilepsy

Quantitative Analysis of Seizure Frequency 1 Week and 6, 12, and 24 Months After Surgery of Epilepsy

Predictive Factors for Success in Surgical Treatment for Partial Epilepsy: A Multivariate Analysis

Surgical Treatment for Partial Epilepsy Among Norwegian Adults

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