“…Consequently, ratiometric probes with NIR fluorescent changes are very attractive to sense and detect important molecules of interest. To date, several fluorescent probes for HSO 3 − /SO 3 2− have been developed based on different approaches such as complexation with amines [15], the selective deprotection of levulinate group [16][17][18][19], the selective reaction with aldehyde [20][21][22][23][24][25][26] and Michael-type additions [27][28][29][30][31][32][33][34][35], however, many of them are intensity-based, in which factors such as instrumental efficiency, the probe concentration, and environmental conditions can interfere with signal output. In addition, almost all of these probes showed emissions only in the visible region, and some of them need to use ultraviolet excitation, which limited their biological applications.…”