A fluorescent sensor-based tripodal-Bodipy for Cu (II) ions: bio-imaging on cells

Abstract

A general synthetic method was improved to synthesize a chemosensor based on a tripodal Bodipy (t-BODIPY) structure. The product and its intermediates products were successfully prepared and fully characterized. The metal ion sensing performance of the tripodal compound was evaluated by. UV/Vis and fluorescence spectroscopies. According to the obtained data, t-BODIPY is a selective and. sensitive fluorescence probe for detection of Cu 2+ ions. in the presence and in the absence of competing ions. This chemosensor presents relatively a low detection limit of 5.4 x10 -7 M for Cu 2+ . Bio-imaging studies on living yeast cells suggest that t-BODIPY has some advantages over other chemosensors to recognize copper (II) ions.

Lanthanide Complexes with Tripodal Ligands

“…Moreover, the latter can be easily varied by using the methods of synthetic organic chemistry. Therefore, it is not surprising that tripodal ligands are widely used in various fields of applied coordination chemistry such as catalysis [1][2][3][4][5][6], chemo sensing [7][8][9], photo- [10][11][12] and electroluminescence [11,13,14], molecular gears and motors production [15,16], biomedical applications [17][18][19][20] and molecular magnetism [12,[21][22][23][24].…”

The Tripodal Ligand’s 4f Complexes: Use in Molecular Magnetism

“…Moreover, the latter can be easily adjusted using the methods of synthetic organic chemistry. Therefore, it is not surprising that tripodal ligands are widely used in various fields of applied coordination chemistry, such as catalysis [1][2][3][4][5][6]; chemo sensing [7][8][9]; photo- [10][11][12] and electroluminescence [11,13,14]; molecular gears and motors construction [15,16]; biomedical applications [17][18][19][20]; and molecular magnetism [12,[21][22][23][24].…”