A fluid—structure interaction study on the biomechanical behaviour of a curved artery with flexible wall

Abstract

Research has shown that thrombus, stenosis, aneurysm, atherosclerosis and other vascular diseases are likely to occur in curved arteries such as aortic arch, coronary artery and cerebral artery. It is found that fatigue damage and failure of arteries are closely associated with the dynamic physiological environment where the arteries are situated. Based on these considerations, the behaviour of curved arteries subjected to a physiological environment is presented in this paper. The fluid-structure interaction (FSI) effect is considered. Wall stress distribution and its variation over time are investigated. Artery deformation regularity throughout the cardiac cycle has been analysed. It is believed that this study may provide insights into clinical research in the future.

Computational estimation of the hemodynamic significance of coronary stenoses in arterial branches deriving from CCTA: A proof-of-concept study

“…The application of Computational Fluid Dynamics (CFD) on the 3D models deriving from CCTA has given the opportunity to calculate important hemodynamic factors such as endothelial pressures and assess the hemodynamic relevance of coronary stenoses. Several attempts have been made and are reported in the literature [3][4][5][6][7][8][9][10][11][12][13]. The main drawback of these methods lies on the fact that a very long computational time is required to complete an assessment of a single patient and in most of the cases, the need of a remote core-laboratory analysis.…”