A fluid-structure interaction study of hemodynamics in arterial bypass-graft anastomoses

Bletsos, G.; Radtke, L.; Düster, A.; Rung, T.

doi:10.23967/eccomas.2022.007

Cited by 1 publication

(2 citation statements)

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“…Therefore, for all subsequent FD-based results a perturbation magnitude of 10 −5 𝛿 is employed. Figures 3 and 4 show FD-based (46) and adjoint-based (43) shape sensitivity estimations for Re = 1.2 and Re = 12, respectively. In specific, computations are realized for both Newtonian and non-Newtonian fluid models.…”

Section: Validation Studiesmentioning

confidence: 99%

“…As concerns the simulation of similar problems, one would usually consider a transient flow or even fluid‐structure interaction, to accurately resolve the flow phenomena, see for example, References 45 and 46. While this goes beyond the scope of this article, we are still interested in optimizing the given geometry under physiological conditions and thus we employ the volumetric flux, shown in Figure 8, as a reference point for the prescription of BCs.…”

Section: Exemplary Applicationmentioning

confidence: 99%

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Adjoint shape sensitivities of blood flows considering non‐Newtonian properties

Bletsos

Kühl

Rung

2023

Numerical Methods in Fluids

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This article discusses the derivation and numerical implementation of an adjoint system, to the primal Navier–Stokes equations, for the computation of shape sensitivities of ducted blood flows considering non‐Newtonian fluid properties. The ever‐growing advancements in blood flow simulations are, naturally, accompanied by an increased interest in the optimization of related medical devices. In the majority of the computational studies, the Newtonian assumption is used to describe the rheology of blood. While this assumption has been shown to satisfactorily capture the flow when it is governed by high shear rates, it falls short at low shear rates. A rich variety of viscosity models has been proposed to tackle this shortcoming. In this article we show how such models can be incorporated into an adjoint system targeting to produce the shape sensitivity which can be used by a gradient‐based optimization method for the minimization of an objective functional. A general formulation of the adjoint equations is proposed, in which contributions of the non‐Newtonian properties explicitly occur. The numerical implementation is discussed and the validity of the method is assessed by means of numerical experiments of steady blood flows in a 2D stenosed duct, where results are compared against second‐order finite‐difference (FD) studies. The proposed methodology is then applied to CAD‐free, gradient‐based shape optimizations of an idealized 3D arterial bypass‐graft operating at three relevant Reynolds numbers. It is observed that the impact of the adjoint viscosity treatment is amplified in low shear‐rate flow regimes while fades for higher shear‐rates, analogous to its primal counterpart.

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Section: Validation Studiesmentioning

confidence: 99%

Section: Exemplary Applicationmentioning

confidence: 99%