A five year follow-up of lung function among chemical workers using flow-volume and impedance measurements

Keman, Soedjajadi; Willemse, Brigitte; Wesseling, Geertjan; Kusters, Eduard; Borm, Paul J. A.

doi:10.1183/09031936.96.09102109

Cited by 13 publications

(9 citation statements)

References 19 publications

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“…Written informed consent was obtained from each worker after evaluation of a self-administered questionnaire on respiratory symptoms, smoking habits and additional questions concerning working history. Lung function was measured using the forced oscillation technique (FOT) and forced expiratory flow volume curves as described previously [Keman et al, 1996]. All subjects completed three impedance measurements and three flow volume curves.…”

Section: Methodsmentioning

confidence: 99%

Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms

et al. 1997

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Section: Methodsmentioning

confidence: 99%

Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms

et al. 1997

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“…Lung function measurements were performed daily between 1:00 and 3:00 p.m. in weeks 1 and 6 and 3 times/week in weeks 2±5 of the observation period as described previously (Keman et al 1996).…”

Section: Lung Functionmentioning

confidence: 99%

Longitudinal changes in inflammatory markers in nasal lavage of cotton workers

Keman

Jetten

Douwes

et al. 1998

International Archives of Occupational and Environmental Health

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“…Similarly, Blanc et al [1993] found that the development of respiratory symptoms following irritant exposures are greater among smoking workers with a history of asthma, and with persistent increases in airway responsiveness without other pulmonary function abnormalities. Recently Keman et al [1996] in a 5-year follow-up of lung function among chemical workers demonstrated a signi®cant decline in forced expiratory volume in the ®rst second (FEV1). This decline was correlated with age, years of employment, and smoking habit.…”

Section: Introductionmentioning

confidence: 99%

Respiratory findings in chemical workers exposed to low concentrations of organic and inorganic air pollutants

Mustajbegović

Zuśkin

et al. 2000

Am. J. Ind. Med.

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Background Occupational exposure to respiratory irritants may effect respiratory function in workers exposed to ambient air pollutants in the workplace. Methods We studied 567 male and 135 female workers employed in two chemical plants in Zagreb, Croatia. Measurements of the ambient concentrations of air pollutants were performed. The mean age of the men was 37 years and mean duration of employment was 12 years; a majority of these workers were smokers. The mean age of the women was 37 years with a mean duration of employment of 14 years; only one‐third of the women smoked. An unexposed group of 340 male and 110 female unexposed workers was also studied. Acute and chronic work related symptoms were recorded for all workers. Ventilatory capacity was measured by recording maximum expiratory flow‐volume (MEFV) curves. Results There were higher prevalences for all chronic respiratory symptoms in exposed than in unexposed workers particularly among women, a majority of which were nonsmokers. Occupational asthma was recorded in three (0.5%) of the men and in two (1.5%) of the women workers. Logistic regression analysis indicated that the presence of chronic respiratory symptoms among exposed workers was primarily associated with the amount of smoking. Additionally, there were high prevalences of acute symptoms during the work shift. Among the chemical workers these were greatest for eye irritation (male: 43.9%; female: 51.9%), dryness of the throat (male: 43.4%; female: 57.0%) and irritation of the throat (male: 37.4%; female: 56.6%). Ventilatory capacity data among the chemical workers demonstrated that most of the measured tests, particularly the FVC and FEV1 were significantly decreased compared to predicted (P < 0.01 or P < 0.05)). In particular nonsmoking women exhibited abnormal lung function. The effect of smoking among exposed workers was demonstrated on all ventilatory capacity tests by regression analysis for all measured respiratory parameters. Both length of exposure and age were correlated with lung function loss for FVC. Measured pollutant levels were for the most part within acceptable standard limits. Conclusions Our data suggest that in this population of chemical workers exposed to low levels of pollutants respiratory symptoms were primarily associated with smoking. Environmental effects, possibly due to an interaction of pollutants were also suggested. Am. J. Ind. Med. 38:431–440, 2000. © 2000 Wiley‐Liss, Inc.

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A five year follow-up of lung function among chemical workers using flow-volume and impedance measurements

Cited by 13 publications

References 19 publications

Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms

Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms

Longitudinal changes in inflammatory markers in nasal lavage of cotton workers

Respiratory findings in chemical workers exposed to low concentrations of organic and inorganic air pollutants

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