A Field Study Assessing Control of Broiler Coccidiosis by Paracox™ Vaccination or by Toltrazuril (Baycox®) Stand-Alone Treatment

Abstract

Toltrazuril (Baycox ® ) stand-alone treatment and Paracox-5 (live attenuated vaccine) were assessed in a field trial for broiler coccidiosis control. The feed did not contain coccidiostats or antimicrobial performance enhancers. Fifteen farms encompassing 90 flocks were followed over three trial episodes (Vaccination-1, Toltrazuril and Vaccination-2). Each episode included two successive flocks/growouts. Daily weight gain, feed conversion ratio, production number and mortality rate were assessed as performance parameters, indicative of coccidiosis control. No cases of clinical coccidiosis were diagnosed during the course of the trial. In general, there was a wide variability in production number within most of the farms, with only a few showing a more consistent performance. Although descriptive statistics showed small differences between the treatments, an analysis of covariance revealed no significant (P < 0.005) treatment effect on any of the four efficacy parameters. The age at processing and farm significantly affected the feed conversion ratio, daily weight gain and production number, but not mortality. Within treatment groups, the feed conversion ratio and daily weight gain were significantly influenced by the month of hatch. It was concluded that a single treatment with toltrazuril is a valuable alternative to vaccination for coccidiosis control in a rotation programme.

Review of triazine antiprotozoal drugs used in veterinary medicine

“…Claeskens, Verdonck, Heesen, Froyman, and Torres () performed a field study to evaluate broiler coccidiosis controlled by toltrazuril in comparison with an Eimeria vaccine. This study also provided a valuable insight into the application of toltrazuril as a preventive measure in field situations.…”

Optimization of Formulation of 5% Toltrazuril Suspension Concentrate and Enhancement of its Bioavailability in Material Engineering

“…Chromatogram of toltrazuril original drug is gotten in the same method as its suspension. On the basis of external standard method, the proportion of toltrazuril is measured by computing the peak area [6].…”