A feasibility study of the clinical effectiveness and cost-effectiveness of individual cognitive behavioral therapy for panic disorder in a Japanese clinical setting: an uncontrolled pilot study

Seki, Yoichi; Nagata, Shinobu; Shibuya, Takayuki; Yoshinaga, Naoki; Yokoo, Mizue; Ibuki, Hanae; Minamitani, Noriko; Kusunoki, Muga; Inada, Yasushi; Kawasoe, Nobuko; Adachi, Soichiro; Yoshimura, Kensuke; Nakazato, Michiko; Iyo, Masaomi; Nakagawa, Akiko; Shimizu, Eiji

doi:10.1186/s13104-016-2262-5

Cited by 19 publications

(17 citation statements)

References 48 publications

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“…The outcome measure of our CBT program was the self-reported severity of PD, as measured by the Panic Disorder Severity Scale (PDSS) (Shear et al, 2001). The self-report form of the PDSS (Houck et al, 2002) measures the severity of PD on a 5-point Likert-type scale ranging from 0 (not severe) to 4 (severe); higher scores indicate more severe PD.…”

Section: Methodsmentioning

confidence: 99%

“…The self-report form of the PDSS (Houck et al, 2002) measures the severity of PD on a 5-point Likert-type scale ranging from 0 (not severe) to 4 (severe); higher scores indicate more severe PD. This scale was adapted from the original, clinician-administered scale (Shear et al, 2001); it is the most frequently used scale for the assessment of PD. The interpretation of the PDSS total score (Furukawa et al, 2009) differed according to the presence or absence of agoraphobia.…”

Section: Methodsmentioning

confidence: 99%

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Imagery rescripting of traumatic memories for panic disorder: an exploratory study

Shibuya

Seki

Nagata

et al. 2018

tCBT

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Imagery rescripting (ImRs) is a psychological intervention designed to change the meaning of images and associated memories and reduce emotional distress. Recent studies have shown that ImRs can be successfully applied to many psychological problems and disorders; however, little has been reported on the application of ImRs for panic disorder (PD). Consequently, we explored the therapeutic effects of ImRs on patients with PD. Fifteen patients with PD received 16 individual cognitive behavioural therapy (CBT) sessions weekly, including one ImRs session. Early traumatic memories associated with recurrent images in panic situations were identified and rescripted to alleviate maladaptive encapsulated beliefs. ImRs ratings (vividness and distress of the images and memories and conviction degree of encapsulated beliefs) were measured prior to and after ImRs. Self-negative contents not directly related to symptoms of panic attack were observed as common themes in the worst meaning of the image, the memory, and in the encapsulated belief. Whilst five (33%) patients had anticipatory anxiety, 10 (67%) patients had other self-negative beliefs. ImRs significantly reduced distress from images, memories and encapsulated beliefs; however, it did not change the vividness of images and memories. There was no significant correlation between the reduction in PD severity over the CBT program and the change in each ImRs rating. The results of this study are promising for certain aspects of panic disorder. However, further research is needed to overcome the limitations of this study.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Imagery rescripting of traumatic memories for panic disorder: an exploratory study

Shibuya

Seki

Nagata

et al. 2018

tCBT

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“…Furthermore, the National Institute for Health and Care Excellence (NICE) guidelines state that CBT is recommended as a first-line treatment in conjunction with selective serotonin re-uptake inhibitors (SSRIs) for PD patients (NICE, 2011). Japanese clinical trials conducted by Seki et al (2016) and Matsumoto et al (2018) also reported that 80% (16/20) and 50% (5/10) of PD cases were in remission, respectively. However, no patients in these studies had developmental disorders such as ASD.…”

Section: Introductionmentioning

confidence: 93%

Blended cognitive behavioural therapy for adolescents with panic disorder co-morbid with autism spectrum disorder: a case study

Hamatani

Matsumoto

Shirayama

2020

tCBT

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Cognitive behavioural therapy (CBT) is an effective treatment for improving anxiety symptoms in patients with autism spectrum disorder (ASD). However, some patients with ASD take extra time for learning, and they can find it hard to change their thinking styles and behaviour due to cognitive deficits. The therapist must be creative when implementing CBT in this context. Here, it may be helpful for the patient with ASD to understand CBT’s concepts by using visual aid material. Blended CBT during which the patient is shown visual aid material with his or her therapist has been suggested as effective for adults without ASD to reduce anxiety. Blended CBT combines face-to-face treatment with internet guided support and resource. Blended CBT may facilitate an understanding of essential knowledge and help people with ASD and anxiety acquire skills based on cognitive behavioural science. However, as far as we know, no previous studies have reported on the use of blended CBT for patients with panic disorder co-morbid with ASD. This study, therefore, consecutively performed 16 blended CBT sessions on a biweekly basis to treat panic disorder (PD) in an adolescent Japanese female co-morbid with ASD. The patient exhibited improvements in PD symptoms and agoraphobia after treatment: the Panic Disorder Severity Scale score decreased from 18 to 2. These results indicate that visual aid-assisted treatment may help patients with impaired imagination and social cognition related to ASD. Furthermore, this study’s therapist notes the need for paced treatments and repeated psychoeducation for patients with impairments in central coherence and cognitive flexibility. Key learning aims (1) Blended CBT may patients with panic disorder (PD) co-morbid with autism spectrum disorder (ASD) to understand concepts based on cognitive behavioural science and symptoms. (2) Blended CBT sessions can each be conducted in approximately 20 min (about one-third of the time needed for typical 45- to 90-min CBT sessions); in other words, it is less burdensome for the patient and therapist. (3) How to adjust blended CBT for those who have low average intelligence quotients (IQ) and/or ASD.

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“…Participants were recruited through clinical referrals and web-based advertisements between April 2014 and March 2015. Fifteen patients with PD (13 women) participated in a single-arm, uncontrolled CBT trial registered in the National UMIN Clinical Trials Registry (ID: UMIN000022693) [ 22 ]. Participants met the criteria for PD according to the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition [ 1 ] and scored ≥ 8 points on the Panic Disorder Severity Scale–Self Report (PDSS-SR) [ 23 ].…”

Section: Main Textmentioning

confidence: 99%

“…Eight clinical psychologists and two psychiatrists administered the CBT; the group was supervised on a weekly basis by a senior supervisor [ 44 ]. Further information regarding the CBT program is provided in Seki et al [ 22 ].…”

Section: Main Textmentioning

confidence: 99%

Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder?

et al. 2018

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ObjectiveMental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group.ResultsPatients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment. Patients completed the Mental Defeat Scale and the Cognitive Flexibility Scale before the intervention, following eight CBT sessions, and following 16 CBT sessions, while the control group did so only prior to receiving CBT (baseline). The patients’ pre-CBT Mental Defeat and Cognitive Flexibility Scale scores were significantly higher on the Mental Defeat Scale and lower on the Cognitive Flexibility Scale than those of the control group participants were. In addition, the average Mental Defeat Scale scores of the patients decreased significantly, from 22.2 to 12.4, while their average Cognitive Flexibility Scale scores increased significantly, from 42.8 to 49.5. These results suggest that CBT can reduce mental defeat and increase cognitive flexibility in patients with PDTrial registration The study was registered retrospectively in the national UMIN Clinical Trials Registry on June 10, 2016 (registration ID: UMIN000022693).Electronic supplementary materialThe online version of this article (10.1186/s13104-018-3130-2) contains supplementary material, which is available to authorized users.

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A feasibility study of the clinical effectiveness and cost-effectiveness of individual cognitive behavioral therapy for panic disorder in a Japanese clinical setting: an uncontrolled pilot study

Cited by 19 publications

References 48 publications

Imagery rescripting of traumatic memories for panic disorder: an exploratory study

Imagery rescripting of traumatic memories for panic disorder: an exploratory study

Blended cognitive behavioural therapy for adolescents with panic disorder co-morbid with autism spectrum disorder: a case study

Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder?

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