A Fatal Case of Induced Cerebral Malaria Due to Plasmodium Falciparum

Amano, Hiroyuki; Yamamoto, Toshio; Sano, Akira; Takahashi, Yasuo; Kurata, Shunichiro; Ichijima, Kunio; Yamabe, Hirohiko

doi:10.2149/tmh1973.4.195

Cited by 2 publications

(2 citation statements)

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“…For several years in Japan, more and more people are coming and going abroad and cases of imported malaria have increased year after year with some unfortunate death (Amano et al, 1976, Ebisawa et al, 1969, Ohtomo et al, 1977. This suggests a number of courses of action for public health and medical treatments (Ebisawa, 1973).…”

Section: Discussionmentioning

confidence: 99%

The Problem and Situation of Anti-Malarial Drug in Japan

Okumura

Nunode

1980

Jap. J. Trop. Med. Hyg.

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Despite several dozens of reports on the importation of malaria every year, it is one of the hardest jobs to obtain anti-malarial drugs in present day Japan, especially in small rural hospitals other than the organization of tropical diseases specialty. This seems to be due to discontinuation of the drug production by the pharmaceutical manufactures because of too scarce demand to make the business profitable, on the one hand, and due to the suit raised in the past by the patients of Chloroquine-retinopathy which, it was claimed, had been caused by excessive doses of the said drug for another disease, on the other. Since the Ministry of Welfare permits use of the drug if it is for malaria, it is hoped that its production be promorted by the Ministry under proper guidance and administration. As a matter of fact, we have cured three cases of malaria patients in 1974 through 1976, with great toils and labour for the acquisition of the drug, indeed. At the moment, one of the private organization is hurrying to map out the institutes of malarial specialty in Japan, for the convenience of patients. And whenever necessary, we save the urgent situation by managing what little stock of the drugs that we have purchased in the foreign countries.

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Section: Discussionmentioning

confidence: 99%

The Problem and Situation of Anti-Malarial Drug in Japan

Okumura

Nunode

1980

Jap. J. Trop. Med. Hyg.

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“…The first nosocomial malaria case was a 21-year-old nurse, most probably transmitted by accidental needle injury from a falciparum malaria patient whom she was taking care of at the hospital (Amano et al, 1976). Chloroquine 600 mg, sulformethoxine 1000 mg and pyrimethamine 50 mg treatment was administered through a stomach tube after she fell into coma but this could not save her life.…”

Section: Reports Of Other Induced Malariamentioning

confidence: 99%

Trends in malaria cases in Japan

Kano

Kimura

2004

Acta Tropica

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Just after World War II, more than 10,000 malaria cases per year were reported in Japan, including indigenous, imported and induced malaria. Malaria has been successfully eradicated since 1961 in Japan and now only imported malaria cases are encountered. However, as the number of Japanese people who are going abroad and also the number of foreigners who are visiting Japan increases (about 16 and 5 millions, respectively, in 2001), so does the chance for Japanese doctors to see imported malaria or transfusion-transmitted malaria cases. In fact, the total number of the patients with acute malaria in Japan has been around 100-150 annually for the last 10 years. Of those, about 75% are Japanese and 25% are foreigners, and about 75% are male and 25% are female. The peak age is in the 20s. Recently, about 45% of patients are Plasmodium falciparum and another 45% Plasmodium vivax infections. The former species is likely to be seen in travelers coming back from African countries and the latter is mainly from Asian countries. The important issue is that patients in Japan have not been diagnosed promptly nor treated properly because doctors in Japan are no longer familiar with tropical medicine. Therefore, some patients are dying from severe malaria as a consequence. As it is, most of the effective medicines for drug-resistant malaria or severe malaria have not been registered in Japan. There is now a need for medical practitioners to focus on travel medicine in Japan.

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A Fatal Case of Induced Cerebral Malaria Due to Plasmodium Falciparum

Cited by 2 publications

References 6 publications

The Problem and Situation of Anti-Malarial Drug in Japan

The Problem and Situation of Anti-Malarial Drug in Japan

Trends in malaria cases in Japan

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