A fast and remote magnetonanothermometry for a liquid environment

Abstract

This study reports on a new approach for remote nanothermometry with short response time (milliseconds) aiming to operate in liquid media using AC susceptibility components of a suspended magnetic nanoparticle subjected to the Brownian relaxation mechanism. A simple, low cost, and accurate system was designed to measure AC susceptibility using an AC magnetic field at small amplitude (6 Oe) and frequency range (5 kHz) superimposed on a weak DC magnetic field (up to 30 Oe). A model based on the AC susceptibility of magnetic nanoparticles (30 nm average diameter) was constructed to describe the temperature measurement sensitivity of the dominated Brownian relaxation time. A new approach for remote nanothermometry was achieved with measured AC susceptibility by the designed system and the proposed model. Our experimental results show that our magnetonanothermometer allows temperature errors lower than 0.3 K with standard deviations lower than 0.1 K in the temperature range from 310 to 320 K.

Simulation Study on Performance Optimization of Magnetic Nanoparticles DC Thermometry Model

“…However, commonly used measuring instruments, such as vibrating sample magnetometer (VSM), or superconducting quantum interferometer (SQUID), are not only poor in real-time, but also costly. Therefore, Zhong et al [ 11 , 18 ] built a fast, convenient and low-cost MNPs magnetization measurement system to realize fast measurement of temperature information. The measurement system uses a Helmholtz coil or solenoid to provide a DC or low-frequency AC excitation magnetic field, and measures the corresponding magnetization signal of MNPs using differential coils.…”

Improving magnetic nanothermometry accuracy through mixing-frequency excitation

“…Magnetic methods for measuring temperature are some of the most promising in vivo temperature imaging methods because they allow measurements to be made within living organisms 6 . Among published magnetic measurement methods, the low-frequency ones with the field frequency lower than 1kHz are based on the Langevin equation [7][8][9][10][11][12][13] , and the middle-frequency ones in the range from 1kHz to 100kHz are based on the Debye model [14][15][16] .…”

“…2(b). As it is difficult to consider both frequency and intensity by using a single-frequency magnetic excitation field, the temperature errors of published methods have difficulties in achieving stable resolutions better than 0.3K 15 .…”

Characterization and Relaxation Properties of a Series of Monodispersed Magnetic Nanoparticles

“…In addition, MIONPs have good temperature performance and can be used as temperature sensors. Some scholars used them to make some progress in the field of magnetic temperature measurement [5,6,7,8,9,10,11]. Due to their low toxicity, biocompatibility, and specificity after surface modification, MIONPs can be used as a target for drug delivery and disease treatment [12,13,14,15].…”