A fast and facile platform for fabricating phase-change materials-based drug carriers powered by chemical Marangoni effect

Hsieh, Meng-Hsuan; Wei, Hao-Ji; Chen, Kuan‐Hung; Wang, Hung-Chen; Yu, C.F.; Lu, Ting-Hsuan; Chang, Yen; Sung, Hsing‐Wen

doi:10.1016/j.biomaterials.2021.120748

Cited by 12 publications

(4 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Generally, the Marangoni stresses arising due to concentration or temperature gradients produce respective surface tension (γ) gradients, → ∇ s γ, that generate near surface liquid flows. These flows are useful and/or cannot be neglected in many technological processes where liquid phases are involved, including in metallurgy [5][6][7], the semiconductor industry [8][9][10], medicine [11,12], biology [13], opto-and microfluidics [14][15][16] and nanotechnology [17,18]. Together with investigations of new multiphase liquid systems in biology and interactions between liquids and nanoparticles, micro-objects and gas bubbles [19] in the presence of structured light, a deep understanding of all aspects of the Marangoni phenomenon is of utmost importance.…”

Section: Introductionmentioning

confidence: 99%

Marangoni Bursting: Insight into the Role of the Thermocapillary Effect in an Oil Bath

Ślemp,

Miniewicz

2023

Fluids

View full text Add to dashboard Cite

Marangoni bursting describes the spontaneous spread of a droplet of a binary mixture of alcohol/water deposited on a bath of oil, followed by its fast spontaneous fragmentation into a large number of smaller droplets in a self-similar way. Several papers have aimed to describe the physical phenomena underlying this spectacular phenomenon, in which two opposite effects, solutal and thermal Marangoni stresses, play competitive roles. We performed investigations of the Marangoni bursting phenomenon, paying attention to the surface temperature changes during bursting and after it. Fragmentation instabilities were monitored using a thermal camera for various initial alcohol/water compositions and at different stages of the process. We uncovered the role of thermocapillary Marangoni flows within the more viscous oil phase that are responsible for outward and inward shrinking of the periphery circle at the final stage of the phenomenon, enabling a more comprehensive understanding of the thermal Marangoni effect. Simulations of the Marangoni thermocapillary effect in an oil bath by solving coupled Navier–Stokes and heat transport equations using the COMSOL Multiphysics software platform support our experimental observations.

show abstract

Section: Introductionmentioning

confidence: 99%

Marangoni Bursting: Insight into the Role of the Thermocapillary Effect in an Oil Bath

Ślemp,

Miniewicz

2023

Fluids

View full text Add to dashboard Cite

show abstract

“…The Marangoni effect − refers to mass transfer along with the interface between two fluids due to the surface tension gradient and demonstrates promising applications in environmental remediation, targeted drug delivery, energy conversion, − self-assembly, , and so on. Because surface tension is sensitive to changes in temperature, temperature variation will lead to a surface tension gradient and the consequent fluid flow, which is called the thermal Marangoni effect. , The photothermal Marangoni effect is considered as an effective way for micro/macro-scale objects to realize the self-propulsion because the light, as ubiquitous and versatile energy, is transmitted in a remote, contactless, and accurate manner. − Under light irradiation, a local surface tension gradient can be generated around the objects and propel the objects to move, showing a simple unidirectional self-propulsion mode.…”

Section: Introductionmentioning

confidence: 99%

“…The Marangoni effect 1−3 refers to mass transfer along with the interface between two fluids due to the surface tension gradient and demonstrates promising applications in environmental remediation, 4 targeted drug delivery, 5 energy conversion, 6−8 self-assembly, 3,9 and so on. Because surface tension is sensitive to changes in temperature, temperature variation will lead to a surface tension gradient and the consequent fluid flow, which is called the thermal Marangoni effect.…”

Section: ■ Introductionmentioning

confidence: 99%

A Light-Powered Triboelectric Nanogenerator Based on the Photothermal Marangoni Effect

Liu

Jiang

Zhu

et al. 2022

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

The photothermal Marangoni effect enables direct light-to-work conversion, which is significant for realizing the self-propulsion of objects in a noncontact, controllable, and continuous manner. Many promising applications have been demonstrated in micro- and nanomachines, light-driven actuators, cargo transport, and gear transmission. Currently, the related studies about photothermal Marangoni effect-induced self-propulsion, especially rotational motions, remain focused on developing the novel photothermal materials, the structural designs, and the controllable self-propulsion modes. However, extending the related research from the laboratory practice to practical application remains a challenge. Herein, we combined the photothermal Marangoni effect-induced self-propulsion with the triboelectric nanogenerator technology for sunlight intensity determination. Photothermal black silicon, superhydrophobic copper foam with drag-reducing property, and triboelectric polytetrafluoroethylene film were integrated to fabricate a triboelectric nanogenerator. The photothermal-Marangoni-driven triboelectric nanogenerator (PMD-TENG) utilizes the photothermal Marangoni effect-induced self-propulsion to realize the relative motion between the triboelectric layer and the electrode, converting light into electrical signals, with a peak value of 2.35 V. The period of the output electrical signal has an excellent linear relationship with the light intensity. The accessible electrical signal generation strategy proposed here provides a new application for the photothermal Marangoni effect, which could further inspire the practical applications of the self-powered system based on the photothermal Marangoni effect, such as intelligent farming.

show abstract

“…Temperature-sensitive hyperbranched polyethyleneimine derivatives increased DOX cell uptake and in vitro cytotoxicity at 40°C ( Sideratou et al, 2018 ). Wrapping vitamin D in medium-chain fatty acids increases its water solubility and keeps it stable in harsh environments ( Hsieh et al, 2021 ). Additionally, the PCMs solid matrix state is eminently suitable for protecting easily decomposed materials or drugs.…”

Section: Introductionmentioning

confidence: 99%

Applications of phase change materials in smart drug delivery for cancer treatment

Bao

et al. 2022

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Phase change materials (PCMs) are materials that are stimulated by the external enthalpy change (temperature) to realize solid-liquid and liquid-solid phase transformation. Due to temperature sensitivity, friendly modification, and low toxicity, PCMs have been widely used in smart drug delivery. More often than not, the drug was encapsulated in a solid PCMs matrix, a thermally responsive material. After the trigger implementation, PCMs change into a solid-liquid phase, and the loading drug is released accordingly. Therefore, PCMs can achieve precise release control with different temperature adjustments, which is especially important for small molecular drugs with severe side effects. The combination of drug therapy and hyperthermia through PCMs can achieve more accurate and effective treatment of tumor target areas. This study briefly summarizes the latest developments on PCMs as smart gate-keepers for anti-tumor applications in light of PCMs becoming a research hot spot in the nanomedicine sector in recent years.

show abstract

A fast and facile platform for fabricating phase-change materials-based drug carriers powered by chemical Marangoni effect

Cited by 12 publications

References 38 publications

Marangoni Bursting: Insight into the Role of the Thermocapillary Effect in an Oil Bath

Marangoni Bursting: Insight into the Role of the Thermocapillary Effect in an Oil Bath

A Light-Powered Triboelectric Nanogenerator Based on the Photothermal Marangoni Effect

Applications of phase change materials in smart drug delivery for cancer treatment

Contact Info

Product

Resources

About