A Fast Anatomical and Quantitative MRI Fetal Exam at Low Field

Aviles, Jordina; Colford, Kathleen; Hall, Megan; Marenzana, Massimo; Uus, Alena; Giles, Sharon; Bridgen, Philippa; Rutherford, Mary; Malik, Shaihan J.; Hajnal, Joseph V.; Tomi‐Tricot, Raphaël; Hutter, Jana

doi:10.1007/978-3-031-17117-8_2

Cited by 3 publications

(3 citation statements)

References 21 publications

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“…The data was denoised using the mrtrix [28] implementation of MP-PCA [29] and direction-averaged for each b-TE combination. We analysed the direction-averaged data using a modified version of the dmipy toolbox [30] We also acquired a separate standard multi-echo gradient echo T2* scan in all participants, as previously reported [31]. The resolution was 3 mm 3 isotropic, FOV = 400×400×[30-55] mm 2 (slices were added or removed as necessary to maximise placental coverage), TR = 9670 ms and the TEs were 80 ms, 222 ms and 365 ms.…”

Section: Methodsmentioning

confidence: 99%

Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function

Slator

Verdera

Tomi‐Tricot

et al. 2023

Preprint

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Purpose: Demonstrating quantitative multi-parametric mapping in the placenta with combined T2*-diffusion MRI at low-field (0.55T). Methods: We present 57 placental MRI scans performed on a commercially available 0.55T scanner. We acquired the images using a combined T2*-diffusion technique scan that simultaneously acquires multiple diffusion preparations and echo times. We processed the data to produce quantitative T2* and diffusivity maps using a combined T2*-ADC model. We compared the derived quantitative parameters across gestation in healthy controls and a cohort of clinical cases. Results: Quantitative parameter maps closely resemble those from previous experiments at higher field strength, with similar trends in T2* and ADC against gestational age observed. Conclusion: Combined T2*-diffusion placental MRI is reliably achievable at 0.55T. The advantages of lower field strength - such as cost, ease of deployment, increased accessibility and patient comfort due to the wider bore, and increased T2* for larger dynamic ranges - can support the widespread roll out of placental MRI as an adjunct to ultrasound during pregnancy.

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Section: Methodsmentioning

confidence: 99%

Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function

Slator

Verdera

Tomi‐Tricot

et al. 2023

Preprint

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“…Recent works 29,30 demonstrated the general feasibility of 0.55T MRI for brain and body imaging as well as several examples of fetal brain SVR reconstruction and functional fetal brain and body data reconstruction 31,32 . Yet, there has been no extensive evaluation of D/SVR performance (or dedicated solutions) to confirm the general feasibility of using 3D reconstruction at 0.55T on a large scale.…”

Section: Fetal Mri At Low Field Strengthmentioning

confidence: 99%

“…The fetal MRI data used in this study were acquired at St. Thomas The acquisitions were performed on a contemporary clinical 0.55T scanner (MAGNETOM Free.Max, Siemens Healthcare, Erlangen, Germany) with 6-element flexible coil (BioMatrix Contour Coil, Siemens Healthcare, Erlangen, Germany) and a 9-element spine coil built into the patient table. The structural T2w stacks were acquired using a dedicated ssTSE sequence optimised for fetal imaging at 0.55T (low-field) 29 with TR = 1460-2500 ms, TE = 105-106 ms, 1.48 mm in-plane resolution, 4.5 mm slice thickness. Each dataset includes 6-12 stacks covering the whole uterus, brain, and trunk regions using standard radiological orientations.…”

Section: Datasets Acquisitionmentioning

confidence: 99%

Scanner-based real-time 3D brain+body slice-to-volume reconstruction for T2-weighted 0.55T low field fetal MRI

Uus,

Neves Silva,

Aviles Verdera

et al. 2024

Preprint

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Purpose: Integrating the SVRTK methods within the Gadgetron framework enables automated 3D fetal brain and body reconstruction in the low-field 0.55T MRI scanner within the duration of the scan. Methods: A deep-learning based, integrated, robust, and deployable workflow from several motion-corrupted individual T2-weighted single-shot Turbo Spin Echo stacks to produce super-resolved 3D reconstructed fetal brain and body is enabled by combining automated deformable and rigid Slice-to-Volume (D/SVR) reconstruction adapted for low field MRI with a real-time scanner-based Gadgetron workflow. Qualitative evaluation of the pipeline in terms of image quality and efficiency is performed in 12 prospectively acquired fetal datasets from the 22-40 weeks gestational age range. Results: The reconstructions were available on average 6:42+-3:13 minutes after the acquisition of the final stack and could be assessed and archived on the scanner console during the ongoing fetal MRI scan. The output image data quality was rated as good to acceptable for interpretation. The additional retrospective testing of the pipeline on 83 0.55T datasets demonstrated stable reconstruction quality for low-field MRI. Conclusion: The proposed pipeline allows scanner-based prospective motion correction for low-field fetal MRI. The main novel components of this work are the compilation of automated fetal and body D/SVR methods into one combined pipeline, the first application of 3D reconstruction methods to 0.55T T2-weighted data, and the online integration into the scanner environment.

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An Automated Pipeline for Quantitative T2* Fetal Body MRI and Segmentation at Low Field

Payette,

Uus,

Aviles Verdera

et al. 2023

Lecture Notes in Computer Science

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A Fast Anatomical and Quantitative MRI Fetal Exam at Low Field

Cited by 3 publications

References 21 publications

Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function

Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function

Scanner-based real-time 3D brain+body slice-to-volume reconstruction for T2-weighted 0.55T low field fetal MRI

An Automated Pipeline for Quantitative T2* Fetal Body MRI and Segmentation at Low Field

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