A fast analytic dose calculation method for arc treatments for kilovoltage small animal irradiators

Marco‐Rius, Irene; Wack, Linda-Jacqueline; Tsiamas, Panagiotis; Tryggestad, E.; Berbeco, R.; Hesser, Juergen; Zygmanski, Piotr

doi:10.1016/j.ejmp.2013.02.003

Cited by 6 publications

(6 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the commissioning task, the gafchromic EBT 2 was used. The calibration curve and dose measurement procedures were performed as reported in previous work [10,11]. …”

Section: Methodsmentioning

confidence: 99%

Comprehensive quality assurance phantom for the small animal radiation research platform (SARRP)

et al. 2015

Self Cite

View full text Add to dashboard Cite

Purpose To develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the Small Animal Radiation Research Platform (SARRP). Methods and materials A QA phantom was developed for carrying out daily, monthly and annual QA tasks including: imaging, dosimetry and treatment planning system (TPS) performance evaluation of the SARRP. The QA phantom consists of 15 (60 × 60 × 5 mm3) kV-energy tissue equivalent solid water slabs. The phantom can incorporate optically stimulated luminescence dosimeters (OSLD), Mosfet or film. One slab, with inserts and another slab with hole patterns are particularly designed for image QA. Results Output constancy measurement results showed daily variations within 3%. Using the Mosfet in phantom as target, results showed that the difference between TPS calculations and measurements was within 5%. Annual QA results for the Percentage depth dose (PDD) curves, lateral beam profiles, beam flatness and beam profile symmetry were found consistent with results obtained at commissioning. PDD curves obtained using film and OSLDs showed good agreement. Image QA was performed monthly, with image-quality parameters assessed in terms of CBCT image geometric accuracy, CT number accuracy, image spatial resolution, noise and image uniformity. Conclusions The results show that the developed QA phantom can be employed as a tool for comprehensive performance evaluation of the SARRP. The study provides a useful reference for development of a comprehensive quality assurance program for the SARRP and other similar small animal irradiators, with proposed tolerances and frequency of required tests.

show abstract

“…For the commissioning task, the gafchromic EBT 2 was used. The calibration curve and dose measurement procedures were performed as reported in previous work [10,11]. …”

Section: Methodsmentioning

confidence: 99%

Comprehensive quality assurance phantom for the small animal radiation research platform (SARRP)

et al. 2015

Self Cite

View full text Add to dashboard Cite

show abstract

“…MC simulations for the SARRP were performed using the EGSnrc code, version 1.44 (2011). Previously, the MC model had been validated against film measurements for 1 mm diameter, 3 × 3 mm 2 , 5 × 5 mm 2 , and 5 × 10 mm 2 in a Plastic Water (CIRS Inc., Norfolk, VA, USA) phantom . The geometry and materials of SARRP were based on its blueprints appropriately modified for matching simulated and measured relative dose profiles.…”

Section: Methodsmentioning

confidence: 99%

“…The Small Animal Radiation Research Platform (SARRP) is a research system for high‐precision preclinical focal irradiation. It has been designed to minimize the technological gap between the current human clinical radiation systems and systems for small animal research . Using on‐board x‐ray cone beam computed tomography (CBCT) for guidance, researchers can localize and conformally irradiate an anatomical target with beams from different orientations to better than 0.2 mm accuracy .…”

Section: Introductionmentioning

confidence: 99%

Validation of GPU‐accelerated superposition–convolution dose computations for the Small Animal Radiation Research Platform

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Current studies highlight considerable dosimetric differences between institutions or from the dose calculation made by the treatment planning systems (TPSs) commissioned by irradiator manufacturers, mainly when the smallest collimators are evaluated 3,5,9 . Experimental methods for x‐ray kV millimetric field dosimetry are mostly based on radiochromic films, and the dose computation methods in TPSs have to rely on film dosimetry, 10 which is very time consuming. In these film dosimetry systems, the energy‐dependent response of the film at the lowest photon energy may give dosimetry uncertainties, as reported by other authors for preclinical irradiators dosimetry 4,5,11–13 …”

Section: Introductionmentioning

confidence: 99%

Integrating X‐ray kV millimetric field dosimetry with a synthetic diamond detector into the treatment planning system commissioning of a preclinical irradiator

Arango

Gómez²,

Alaminos-Bouza

et al. 2021

Medical Physics

View full text Add to dashboard Cite

Small animal irradiators are equipped with x-ray beams and cone collimators with millimeter dimensions to be used in preclinical research. The use of small fields in the kV energy range may require the application of energy-dependent, field size-dependent, or depth-dependent correction factors to the dosimetric data acquired for treatment planning system (TPS) commissioning purposes to obtain accurate dose values. Considering that these corrections are also detector dependent, the suitability of a synthetic single-crystal diamond detector for small-field relative dosimetry in a preclinical irradiator (220-kVp) was evaluated to avoid the necessity of applying correction factors during TPS commissioning. Methods: The detector response was assessed during the transition for field sizes ranging from 20 × 20 mm 2 to 3 × 3 mm 2 , using the small animal radiation research platform (SARRP). The percentage depth dose distributions (PDDs), lateral profiles and output factors (OFs) were measured. The PDDs for the synthetic diamond detector were compared to the distributions acquired using a small-volume microchamber (0.016 cm 3 ) and with Monte Carlo calculations using the MC3D in-house software package. The profiles and OFs were compared to the data from a silicon solid-state detector and to radiochromic film data provided by the manufacturer; for the OF determination, measurements made using a microchamber were added for comparison. The performance of several detectors used as references was previously validated for relative dosimetry in preclinical irradiators. A commercial TPS was commissioned for the factor-based algorithm, using the data acquired with the diamond detector, and no additional correction factors were applied. To verify the performance of the TPS and the accuracy of the dosimetric methodology, radiochromic film irradiation in water was conducted, and two-dimensional (2D) dose distributions in the coronal and axial planes were compared under different gamma criteria. Results: Compared with the microchamber and MC3D distributions, the agreement of the PDDs using the synthetic diamond detector was better than 2%. The profile data exhibited very good agreement compared with the data from the silicon detector, with an average and a maximum difference of 0.31 and 0.39 mm in the penumbras, respectively. Compared with the data from the radiochromic film, the average and maximum differences were equal to 0.77 and 0.89 mm, respectively. Very good agreement, within 1%, was obtained between the OFs measured with the synthetic diamond detector and the radiochromic film, compared only for the cone collimators. The validation of the TPS commissioning using gamma criteria compared to film showed an average passing rate of 100% and 93.2% with a global gamma criterion of 1 mm/3% for the coronal and axial planes, respectively, including the 3 × 3 mm 2 field size and penumbra regions. Conclusions: Synthetic diamond is a suitable detector for the complete relative dosimetry of small x-ray fields. The commissioning of the TPS ...

show abstract

A fast analytic dose calculation method for arc treatments for kilovoltage small animal irradiators

Cited by 6 publications

References 13 publications

Comprehensive quality assurance phantom for the small animal radiation research platform (SARRP)

Comprehensive quality assurance phantom for the small animal radiation research platform (SARRP)

Validation of GPU‐accelerated superposition–convolution dose computations for the Small Animal Radiation Research Platform

Integrating X‐ray kV millimetric field dosimetry with a synthetic diamond detector into the treatment planning system commissioning of a preclinical irradiator

Contact Info

Product

Resources

About