A Facile Synthesis and Antitumor Activity of Novel 2-Aryl-2,3- dihydro-1<i>H</i>-pyrrolo[3,4-<i>b</i>]quinoxalin-1-ones

Xi, Qi; Jiang, Wenting; Wang, Hongxue; Liu, Jia; Sun, Fuze; Wen, Baohan; Zhao, Xin-Yue; Gao, Siyang; Li, Yang

doi:10.1080/10406638.2021.1881130

Cited by 1 publication

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“…Quinoxaline derivatives are used as bio-screening agents and fair enough efforts have been devoted for their synthesis, many efforts have been devoted for synthesis of drug hybrids which have benzofuran and quinoxaline structures in a molecule. In this perspective, Li et al presented expeditious work for the facile synthesis of quinoxaline-based isoindolin-1-ones (189a-q) (Scheme 42) [75].…”

Section: Ultrasound In Synthesis Of Pyridine and Fused Pyridine Ringsmentioning

confidence: 99%

Ultrasound assisted synthesis of 5–7 membered heterocyclic rings in organic molecules

Shabir

Shafique

Saeed

2022

Journal of Heterocyclic Chem

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Ultrasound synthesis is a powerful technique that is being used increasingly to accelerate organic reactions as a green synthetic approach. Ultrasonication has offered advantages over conventional methods in terms of enhanced yields, shorter reaction time, high selectivity and minimal side reaction. The current investigation is the review of papers published from 2016 to 2022 for the synthesis of organic heterocycles under the effect of ultrasound irradiation. It is a comprehensive compilation of sonochemical processes as a versatile technique to achieve synthesis of numerous organic scaffolds from simple carbocyclic compounds to complex and biologically active heterocyclic structural molecules. This review encompasses the examples of ultrasound supported synthetic reactions of multicomponent one pot processes as well as different steps flow synthesis. Ultrasound assisted synthesis have been proved as an ecofriendly and benign approach for the synthesis of 5-7 membered heterocyclic rings, with one to three hetero atoms. Moreover Ultrasound synthesis has offered excellent yield in a vast majority of reactions under mild conditions without involving complicated purification procedures.

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Section: Ultrasound In Synthesis Of Pyridine and Fused Pyridine Ringsmentioning

confidence: 99%

Ultrasound assisted synthesis of 5–7 membered heterocyclic rings in organic molecules

Shabir

Shafique

Saeed

2022

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

show abstract

A Facile Synthesis and Antitumor Activity of Novel 2-Aryl-2,3- dihydro-1H-pyrrolo[3,4-b]quinoxalin-1-ones

Cited by 1 publication

References 38 publications

Ultrasound assisted synthesis of 5–7 membered heterocyclic rings in organic molecules

Ultrasound assisted synthesis of 5–7 membered heterocyclic rings in organic molecules

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