A facile route to the synthesis of spherical poly(acrylic acid) brushes via RAFT polymerization for high-capacity protein immobilization

Qu, Zhenyuan; Hu, Fenglin; Chen, Kaimin; Duan, Zongqiang; Gu, Hongchen; Xu, Hong

doi:10.1016/j.jcis.2013.02.001

Cited by 60 publications

(56 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The synthesized GO exhibited a π–π* transition centered at 231 nm corresponding to CC bonds and a shoulder band at 300 nm which corresponds to the n–π* transition of CO moieties . On the other hand, the absorption profile of the RAFT CTA displayed two bands centered at 233 and 311 nm which is similar to the reported literature . The UV–vis profile of GO–RAFT is intermediate to that of pure GO and RAFT CTA.…”

Section: Resultssupporting

confidence: 83%

Graphene Oxide–Poly(ethylene glycol) methyl ether methacrylate Nanocomposite Hydrogels

Mangadlao

Huang

Foster

et al. 2015

Macro Chemistry & Physics

View full text Add to dashboard Cite

In this paper, covalently linked graphene oxide–poly(ethylene glycol) methyl ether methacrylate–reversible addition‐fragmentation chain transfer (GO–PEGMEMA–RAFT) and physically mixed GO–PEGMEMA hydrogel nanocomposites are synthesized. Spectroscopic and imaging techniques such as UV–vis, Fourier transform infrared, Raman spectroscopy, and transmission electron microscopy show that the PEGMEMA is successfully grafted on GO sheets. The rheology of the nanocomposites is studied by small angle oscillatory shear, which shows a competition between reinforcement and lubrication behavior of GO. In the case where lubrication effect dominates reinforcement, the covalently linked GO–PEGMEMA–RAFT has higher G′ compared to the physically mixed GO‐PEGMEMA. Hence, in the covalently linked system, the grafted polymer chains appear to minimize the lubrication effect.

show abstract

Section: Resultssupporting

confidence: 83%

Graphene Oxide–Poly(ethylene glycol) methyl ether methacrylate Nanocomposite Hydrogels

Mangadlao

Huang

Foster

et al. 2015

Macro Chemistry & Physics

View full text Add to dashboard Cite

show abstract

“…RAFT polymerization is initiated using a conventional radical‐initiation method and is mediated by a chain transfer agent (Z‐(C=S)‐SR), in which Z is a stabilizing group that affects the reactivity of thiocarbonyl group toward free radical addition, and R is a leaving group that becomes a radical and starts the propagation of a chain after a fragmentation reaction. For SI‐RAFT polymerization, surface is modified by either initiators or CTAs which can be fixed on surfaces through Z‐group or R‐group . Z‐group approach allows R groups to become free species generating chains in bulk solution.…”

Section: Introductionmentioning

confidence: 99%

Accelerated brush growth on nanoparticle surfaces by reversible addition‐fragmentation chain transfer polymerization

Jiao

Akcora

2014

J. Polym. Sci. Part A: Polym. Chem.

View full text Add to dashboard Cite

It is now well established that controlling the grafted chain lengths and densities on nanoparticle surfaces determines the effective interactions between particles, and their assembly. Here, we present unusual kinetic results for achieving grafted chain lengths longer than the free chains using reversible addition‐fragmentation chain transfer (RAFT) polymerization and discuss the limitations to obtaining polymer grafting density higher than ∼0.06 chains/nm2. We observe that surface initiated polymerization grows faster than the free chains in solution with high RAFT agent coverage (1.95 agents/nm2) on nanoparticles. The time‐dependence of graft density suggests that activation of the anchored chain transfer agent (CTA) is limited by the diffusion of macro‐radicals within growing grafts. Thus, radical transfer and exchange reactions become inefficient between grafts and free polymer, and convert the surface‐initiated RAFT mechanism to a free radical polymerization. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 1700–1705

show abstract

“…44 Following this strategy, the addition of free RAFT agent was widely applied for surface-initiated RAFT polymerizations. 44,114,[200][201][202]206 Another issue was noticed in the fundamental article by Fukuda. Gel permeation chromatography (GPC) spectra of the grafted polymers showed a shoulder which was assigned to dead chains from the recombination of polymer radicals (solid curves in Figure 9b).…”

Section: Surface-initiated Raft From Silica Nanoparticlesmentioning

confidence: 98%

“…201 Xu et al prepared well-defined PAA brushes from silica nanoparticles via surface-initiated RAFT polymerization. 202 A RAFT agent functionalized silane, MBET ( Table 2, entry 3), was designed and anchored onto silica nanoparticles by its R-group. The authors studied the structure and responsiveness of the PAA grafted silica nanoparticles thoroughly by TEM, dynamic light scattering (DLS), GPC, thermogravimetric analysis (TGA), and conductometric titration.…”

Section: Surface-initiated Raft From Silica Nanoparticlesmentioning

confidence: 99%

Surface-initiated controlled radical polymerizations from silica nanoparticles, gold nanocrystals, and bionanoparticles

2015

View full text Add to dashboard Cite

In recent years, core/shell nanohybrids containing a nanoparticle core and a distinct surrounding shell of polymer brushes have received extensive attention in nanoelectronics, nanophotonics, catalysis, nanopatterning, drug delivery, biosensing, and many others. From the large variety of existing polymerization methods on the one hand and strategies for grafting onto nanoparticle surfaces on the other hand, the combination of grafting-from with controlled radical polymerization (CRP) techniques has turned out to be the best suited for synthesizing these well-defined core/shell nanohybrids and is known as surface-initiated CRP. Most common among these are surface-initiated atom transfer radical polymerization (ATRP), surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization, and surface-initiated nitroxide-mediated polymerization (NMP). This review highlights the state of the art of growing polymers from nanoparticles using surface-initiated CRP techniques. We focus on mechanistic aspects, synthetic procedures, and the formation of complex architectures as well as novel properties. From the vast number of examples of nanoparticle/polymer hybrids formed by surface-initiated CRP techniques, we present nanohybrid formation from the particularly important and most studied silica nanoparticles, gold nanocrystals, and proteins which can be regarded as bionanoparticles

show abstract

A facile route to the synthesis of spherical poly(acrylic acid) brushes via RAFT polymerization for high-capacity protein immobilization

Cited by 60 publications

References 28 publications

Graphene Oxide–Poly(ethylene glycol) methyl ether methacrylate Nanocomposite Hydrogels

Graphene Oxide–Poly(ethylene glycol) methyl ether methacrylate Nanocomposite Hydrogels

Accelerated brush growth on nanoparticle surfaces by reversible addition‐fragmentation chain transfer polymerization

Surface-initiated controlled radical polymerizations from silica nanoparticles, gold nanocrystals, and bionanoparticles

Contact Info

Product

Resources

About