A facile, low-cost bimetallic iron–nickel MOF nanozyme-propelled ratiometric fluorescent sensor for highly sensitive and selective uric acid detection and its smartphone application

Han, Jiawen; Zhang, Yuwei; Lv, Xujuan; Fan, Daoqing; Dong, Shaojun

doi:10.1039/d3nr05028a

Cited by 7 publications

(1 citation statement)

References 65 publications

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“…Therefore, the detection of UA is vital for health monitoring and disease diagnosis. Han and co-workers reported the first MOF nano-enzymatic source proportional fluorescent UA sensor based on the Fe 3 Ni-MOF-NH 2 -propelled UA/uricase/phthalimide tandem catalytic reaction [ 117 ]. Unlike previous reports, this work exploited both the peroxidase-like and fluorescence properties of Fe 3 Ni-MOF-NH 2 .…”

Section: Biosensing Applications Of Bimetallic Cpsmentioning

confidence: 99%

Bimetallic Coordination Polymers: Synthesis and Applications in Biosensing and Biomedicine

Sun,

Ma,

Ahmad

et al. 2024

Biosensors

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Bimetallic coordination polymers (CPs) have two different metal ions as connecting nodes in their polymer structure. The synthesis methods of bimetallic CPs are mainly categorized into the one-pot method and post-synthesis modifications according to various needs. Compared with monometallic CPs, bimetallic CPs have synergistic effects and excellent properties, such as higher gas adsorption rate, more efficient catalytic properties, stronger luminescent properties, and more stable loading platforms, which have been widely applied in the fields of gas adsorption, catalysis, energy storage as well as conversion, and biosensing. In recent years, the study of bimetallic CPs synergized with cancer drugs and functional nanomaterials for the therapy of cancer has increasingly attracted the attention of scientists. This review presents the research progress of bimetallic CPs in biosensing and biomedicine in the last five years and provides a perspective for their future development.

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Section: Biosensing Applications Of Bimetallic Cpsmentioning

confidence: 99%

Bimetallic Coordination Polymers: Synthesis and Applications in Biosensing and Biomedicine

Sun,

Ma,

Ahmad

et al. 2024

Biosensors

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Nanozyme‐Enabled Biomedical Diagnosis: Advances, Trends, and Challenges

Tian,

Li,

Tang

et al. 2024

Adv Healthcare Materials

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As nanoscale materials with the function of catalyzing substrates through enzymatic kinetics, nanozymes are regarded as potential alternatives to natural enzymes. Compared to protein‐based enzymes, nanozymes exhibit attractive characteristics of low preparation cost, robust activity, flexible performance adjustment, and versatile functionalization. These advantages endow them with wide use from biochemical sensing and environmental remediation to medical theranostics. Especially in biomedical diagnosis, the feature of catalytic signal amplification provided by nanozymes makes them function as emerging labels for the detection of biomarkers and diseases, with rapid developments observed in recent years. To provide a comprehensive overview of recent progress made in this dynamic field, here an overview of biomedical diagnosis enabled by nanozymes is provided. This review first summarizes the synthesis of nanozyme materials and then discusses the main strategies applied to enhance their catalytic activity and specificity. Subsequently, representative utilization of nanozymes combined with biological elements in disease diagnosis is reviewed, including the detection of biomarkers related to metabolic, cardiovascular, nervous, and digestive diseases as well as cancers. Finally, some development trends in nanozyme‐enabled biomedical diagnosis are highlighted, and corresponding challenges are also pointed out, aiming to inspire future efforts to further advance this promising field.

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Sensitive colorimetric detection of Vibrio vulnificus based on target-induced shielding against the peroxidase-mimicking activity of CeO2@PtRu nanozyme

Xu,

Xie,

et al. 2024

Food Chemistry

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A facile, low-cost bimetallic iron–nickel MOF nanozyme-propelled ratiometric fluorescent sensor for highly sensitive and selective uric acid detection and its smartphone application

Abstract: As a kind of well-known disease biomarker, uric acid (UA) is closely associated with normal metabolism and health. Despite versatile nanozymes facilitated the analysis of UA, most previous works can...

Cited by 7 publications

References 65 publications

Bimetallic Coordination Polymers: Synthesis and Applications in Biosensing and Biomedicine

Bimetallic Coordination Polymers: Synthesis and Applications in Biosensing and Biomedicine

Nanozyme‐Enabled Biomedical Diagnosis: Advances, Trends, and Challenges

Sensitive colorimetric detection of Vibrio vulnificus based on target-induced shielding against the peroxidase-mimicking activity of CeO2@PtRu nanozyme

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