A Facile Fabrication of Poly‐ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol

Abstract

An electrochemical sensor based on poly‐ethionine (Poly‐ET) film modified glassy carbon electrode was developed for sensitive and simultaneous sensing of dopamine (DA) and paracetamol (PA). The electropolymerization of ethionine monomer was carried out to modify the electrode. The modified electrode was characterized by using scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. The Poly‐ET/GCE exhibited excellent electrocatalysis towards the sensing of DA and PA. Poly‐ET/GCE showed a linear increase of current response with increase concentration of DA and PA ranging from 0.1 μM–60 μM and 0.1 μM–180 μM, respectively. The LODs were found to be 7 nM and 18 nM (S/N=3) for DA and PA, respectively. This electrochemical sensor was successfully utilized for the detection of DA and PA in pharmaceutical samples.

Actualities in immunological markers and electrochemical sensors for determination of dopamine and its metabolites in psychotic disorders (Review)

“…The performance characteristics of other recently reported electrochemical sensors for DA detection are summarized in Table I (73)(74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86)(87)(88)(89)(90).…”

Sensitive and selective determination of paracetamol in antipyretic children's syrup with a polyglycine modified glassy carbon electrode

“…The surface of the modied sensor is active for quantication of various bioactive molecules. 63,64 In recent years, poly (amino acids) have been used as modiers in the eld of electroanalysis, especially polyglycine (PolyGly) has been used in the determination of many pharmaceutical compounds. 65 Many studies describe the electropolymerization of glycine by cyclic voltammetry (CV) on the surface of carbon electrodes.…”

“…The surface of the modified sensor is active for quantification of various bioactive molecules. 63,64…”