A Facile and Expeditious Microwave-Assisted Synthesis of Furo[3,4-b]indeno[2,1-f]quinolin-1-one DerivativesviaMulticomponent Reaction

Peng, Juhua; Jia, Runhong; Ma, Ning; Zhang, Ge; Wu, Feiyue; Cheng, Chuang; Tu, Shu‐Jiang

doi:10.1002/jhet.965

Cited by 10 publications

(1 citation statement)

References 35 publications

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“…Furoindenoquinolin-1-one derivatives 35 were prepared when 9H-fluoren-2-amine was condensed with tetronic acid and benzaldehydes in acetic acid under microwave irradiation for 10 min (Scheme 26) [75].…”

Section: Synthesis Of Quinoline By Microwave Irradiationmentioning

confidence: 99%

Current progress toward synthetic routes and medicinal significance of quinoline

Shehab,

Amer,

Elsayed

et al. 2023

Med Chem Res

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Quinoline motifs are essential in several pharmacological active heterocyclic compounds due to their various applications in medicinal and industrial chemistry. Furthermore, there are greater societal expectations in the current scenario that synthetic and medicinal chemists should produce greener and more sustainable chemical processes. Therefore, this mini-review article highlights the traditional and green synthetic approaches of quinoline and its analogs, including multicomponent one-pot reactions and solvent-free reaction conditions utilizing microwave and ultraviolet irradiation-promoted synthesis using eco-friendly and safe reusable catalysts, in addition to discussing the medicinal importance of quinoline derivatives such as anticancer, antioxidant, anti-inflammatory, antimalarial, anti-SARS-CoV-2, and antituberculosis activities within the period from 2011 till 2021. Therefore, the quinoline scaffolds signify a unique class of pharmacophores present in various therapeutic agents.

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Section: Synthesis Of Quinoline By Microwave Irradiationmentioning

confidence: 99%

Current progress toward synthetic routes and medicinal significance of quinoline

Shehab,

Amer,

Elsayed

et al. 2023

Med Chem Res

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show abstract

Multicomponent Synthesis of Heterocycles

2022

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ChemInform Abstract: A Facile and Expeditious Microwaves‐Assisted Synthesis of Furo[3,4‐b]indeno[2,1‐f]quinolin‐1‐one Derivatives via Multicomponent Reaction.

Peng

Jia

et al. 2013

ChemInform

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A Facile and Expeditious Microwaves-Assisted Synthesis of Furo[3,4-b]indeno[2,1-f]quinolin-1-one Derivatives via Multicomponent Reaction. -This rapid and direct method offers a simple route for the one-pot, three-component synthesis of highly functionalized fused heterocycles in high yields. Valuable features of this approach include clean reactions, a broader substrate scope, operational simplicity, and increased safety for small-scale high-speed synthesis. -(PENG, J.-H.; JIA, R.-H.; MA, N.; ZHANG, G.; WU, F.-Y.; CHENG, C.; TU*, S.-J.; J. Heterocycl. Chem. 50 (2013) 4, 899-902, http://dx.

show abstract

A Facile and Expeditious Microwave-Assisted Synthesis of Furo[3,4-b]indeno[2,1-f]quinolin-1-one DerivativesviaMulticomponent Reaction

Cited by 10 publications

References 35 publications

Current progress toward synthetic routes and medicinal significance of quinoline

Current progress toward synthetic routes and medicinal significance of quinoline

Multicomponent Synthesis of Heterocycles

ChemInform Abstract: A Facile and Expeditious Microwaves‐Assisted Synthesis of Furo[3,4‐b]indeno[2,1‐f]quinolin‐1‐one Derivatives via Multicomponent Reaction.

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