A dysregulated bile acids pool is associated with metabolic syndrome and gut microbial dysbiosis in early adolescence
Yesenia Mancera‐Hurtado,
Blanca E. Lopez‐Contreras,
Regina Flores‐Lopez
et al.
Abstract:Objective: The increased prevalence of childhood metabolic syndrome (MetS) is a public health issue. It has been shown that a dysregulated bile acid (BA) profile could be involved in the development of MetS, in which the gut microbiota could have a significant role in BA levels. This study aimed to evaluate differences in serum BA levels in children with and without MetS and whether these levels were associated with gut microbial composition.Methods: A total of 100 children aged 10 to 12 years were enrolled in… Show more
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