A dual-signal electrochemiluminescence immunosensor for high-sensitivity detection of acute myocardial infarction biomarker

Electrochemiluminescence biosensor for cardiac troponin I with signal amplification based on a MoS2@Cu2O–Ag-modified electrode and Ce:ZnO-NGQDs

“…In addition, the incubation time of Ab 2 can directly affect the strength of the ECL. 41 The impact of the Ab 2 incubation time from 10 to 100 min on the ECL intensity was explored (Fig. 5D).…”

Point-of-care testing of infectious diseases: recent advances

“…In recent years, the development of various novel labels, the advances in microfabrication technology, and the integration of different technologies have also contributed to advances in immunological assays, such as faster detection time, better detection performance, and easier methods for reading results, as well as making portable detection platforms based on LFIA, sensors and microfluidic chips accessible. [21][22][23][24][25][26] The antigen-antibody reaction is performed on the surface of the chip channel, at the sensing interface of the sensor, or on the paperbased material, and then the signal readout method is selected according to the properties of the labels. Immunological methods based on different labels share the most procedures of classical ELISA.…”

Electrochemiluminescence Biosensor for Estrogen-Related Receptor Alpha (ERRα) Based on Target-Induced Change of the Steric Hindrance Effect of an Antibody-Modified Electrode

“…The steric hindrance effect can influence the content of electroactive compounds reaching the surface of the working electrode. This phenomenon has been applied to characterize the status of the electrode surface frequently. − Recently, this characteristic had been coupled with ECL detection to develop some sensitive ECL biosensors. For example, our group developed a signal on the sensitive ECL biosensor for DNA detection through coupling the steric hindrance effect of Au nanocages with the Exo III-assisted target recycling amplification strategy; the presence of targets leads to the decrease of the amount of Au nanocages modified on the electrode surface, and the steric hindrance decreases too, so more amount of the ECL indicator (tris­(2,2′-bipyridine) dichlororuthenium­(II) hexahydrate, Ru­(bpy) 3 2+ ) can reach the electrode surface, and an enhanced ECL signal can be detected .…”