A double-blind study on clinical effects of Dexaltin ointment

Comparison between self‐formulation and compounded‐formulation dexamethasone mouth rinse for oral lichen planus: a pilot, randomized, cross‐over trial

“…31 Although not designed for the oral environment, products made for systemic, cutaneous, and nasal preparations, such as topical dexamethasone in the form of a crushed tablet mouth rinse, aerosols, suspensions, and ointments, have shown to be clinically effective in the treatment of OLP and OLR. 32,33 There is extensive documentation of the use of dexamethasone in OLP and other mucocutaneous inflammatory conditions. [32][33][34] Evidence suggests that dexamethasone in the form of a mouth rinse can significantly decrease the production of locally-produced proinflammatory cytokines to give satisfactory clinical outcomes in OLP.…”

“…32,33 There is extensive documentation of the use of dexamethasone in OLP and other mucocutaneous inflammatory conditions. [32][33][34] Evidence suggests that dexamethasone in the form of a mouth rinse can significantly decrease the production of locally-produced proinflammatory cytokines to give satisfactory clinical outcomes in OLP. 6,19 The use of a mouth rinse as topical therapy for OLP is thought to be more beneficial than other forms, as it is a more efficient means for targeting larger areas, is easily applied to posterior areas of the mouth and extensile surfaces, and most importantly, lowers systemic absorption rates compared with oral ingestion.…”

“…Although not designed for the oral environment, products made for systemic, cutaneous, and nasal preparations, such as topical dexamethasone in the form of a crushed tablet mouth rinse, aerosols, suspensions, and ointments, have shown to be clinically effective in the treatment of OLP and OLR . There is extensive documentation of the use of dexamethasone in OLP and other mucocutaneous inflammatory conditions .…”