A double-blind, placebo-controlled, multi-dose evaluation of the acute                 behavioural effects of guaraná in humans

Haskell, Crystal F.; Kennedy, David O.; Wesnes, Keith; Milne, Anthea; Scholey, Andrew

doi:10.1177/0269881106063815

Cited by 95 publications

(100 citation statements)

References 11 publications

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“…One often observed consequence of caffeine ingestion is improved memory for material, such as a list of words (anderson & revelle, 1994;rusted, 1994;Warburton, 1995;Scholey & kennedy, 2004;haskell, kennedy, Wesnes, milne, & Scholey, 2007). Sometimes, caffeine has no effect or even a detrimental effect on memory, as when the test is a short-term memory test rather than a delayed memory test (e.g., anderson, revelle, & Lynch, 1989;Warburton, 1995) or when the dosage level is too low (e.g., Smith, Sturgess, & Gallagher, 1999).…”

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confidence: 99%

Caffeine's Effects on True and False Memory

Capek

Guenther

2009

Psychol Rep

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Caffeine's effects on recall of word lists were investigated using the Deese-Roediger-McDermott (DRM) paradigm. College students were administered either 200 mg of caffeine or a 250-mg lactose placebo; after 30 min., they were tested on recall using six word lists. Words of each list were semantically related to a single word (a "critical lure") that was not presented in the list. Participants administered caffeine recalled more list words and more critical lures than participants administered lactose. Recall of list words was negatively correlated with recall of critical lures. Caffeine appears to intensify the strength of connections among list words and critical lures, thereby enhancing both true and false memory.

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confidence: 99%

Caffeine's Effects on True and False Memory

Capek

Guenther

2009

Psychol Rep

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“…Ginseng's effects on cognition are unclear, but are likely to be nonnegative (H. R. Lieberman, 2001) while it has not been studied as an ergogenic aid. Guaraná has been shown to enhance secondary memory in one study (Haskell et al, 2007), though comprehensive research on its effects on cognition or exercise is lacking. Similarly, there is no research on inositol's unique effects on exercise or cognitive performance.…”

Section: Resultsmentioning

confidence: 99%

“…Participants receiving doses of 37.5 mg or 75 mg of guaraná extract (approximately 11% caffeine) 1 to 6 hours prior to cognitive testing had improvements in secondary memory compared to placebo, though no effects were seen for speed or accuracy of attention, speed of memory, or working memory (Haskell et al, 2007). Other research on the effectiveness of guaraná is limited in that guaraná is always co-administered with caffeine.…”

Section: Guaranámentioning

confidence: 99%

Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists

Lassiter

Kammer

Burns

et al. 2012

Journal of Caffeine Research

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Dedication This work is dedicated to those who have supported me outside of my graduate studies over the last few years. My family deserves as much credit as anyone for the work generated as part of this study. Namely, Kristin Bagby, Christine Lassiter, Mechelle Lassiter, Bette Rose Ryan, and Michele Poague deserve recognition; without them I would not have been able to work as tirelessly as I have on this project. v Acknowledgements Many individuals contributed significantly to the completion of this project. Though the thesis is my own, the project is a result of a team effort. First and foremost Lynne Kammer helped me every step of the research process, from study design, to data collection, and proofreading. Zhenping Ding played another critical role in training and overseeing the completion of the biochemistry techniques used as part of this work. Assays were completed is listed last, his help on this and other projects that I have been a part of is understated and I commend him for being such a hard-working and loyal individual. My graduate studies have been made possible through the concerted efforts of the entire kinesiology staff at the University of Texas and I would like to recognize the contributions to my education made by Ivy have served as readers for my thesis and for this I owe them recognition. Lastly I would like to thank the sponsor of my research, SWSS law, and the participants who were willing to ride their bikes in the lab for the sake of expanding our scientific understanding. vi Abstract Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists David Gray Lassiter, MS KIN The University of Texas at Austin, 2012 Supervisor: John Ivy This study investigated the effectiveness of an energy drink (ED) in enhancing cycling time-trial performance, and cognitive performance at rest, during moderate-intensity exercise, and after exercise. The protocol was double-blind, randomized, placebo-controlled, two-period, and within-subjects. The treatments were ED containing caffeine and carbohydrate, and a caffeine-free non-caloric flavored placebo beverage (PLA). Exercise performance was measured by time to finish a simulated 35 km time-trial course. Cognitive performance was measured by a Stroop task, a tapping task, a reaction time task, and an executive function task consisting of both tapping and reaction time. The effects of ED on blood markers were also assessed. Race performance was enhanced by an average of 3% when participants had ED compared to PLA without a difference in rating of perceived exertion (RPE). Performance was improved by ED even in participants that arrived to the lab with elevated blood caffeine concentrations. Both before and after the exercise, ED resulted in more taps per second in the tapping task. After receiving ED, plasma insulin spiked, there was a fall in free fatty acids (FFA) and vii blood glucose remained unchanged. Exercise onset caused a drop in blood glucose when participants consumed ED, though glucose returned to a level that was not di...

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“…Only one improvement was observed, a significant effect of guaraná on mosaic performance at 5 months (171) . More recently a randomised, double-blind, placebocontrolled, counterbalanced study examined the effects of a range of doses (37·5, 75, 150 and 300 mg) of guaraná (standardised to 11 % caffeine), over the course of 6 h (172) . Improvements to a 'secondary memory' factor following both 37·5 and 75 mg guaraná were observed, as well as increased self-rated 'alertness' following the highest dose and increases in self-rated 'contentment' following all doses of guaraná.…”

Section: Guaraná (Paullinia Cupana)mentioning

confidence: 99%

Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants

et al. 2013

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Research into the cognitive and mood effects of caffeine in human subjects has highlighted some fairly robust and well-accepted effects. However, the majority of these studies have focused on caffeine in isolation; whilst caffeine is normally consumed in the form of plantderived products and extracts that invariably contain other potentially bioactive phytochemicals. The aim of the present review is to consider the possible mechanisms of action of co-occurring phytochemicals, and any epidemiological evidence suggesting that they contribute to potential health benefits ascribed to caffeine. Intervention studies to date that have been conducted to explore the effects on brain function of the non-caffeine components in caffeine-bearing plants (coffee, tea, cocoa, guaraná), either alone or in combination with caffeine, will also be summarised. Research is beginning to accumulate showing independent effects for several of the phytochemicals that co-occur with caffeine, and/or a modulation of the effects of caffeine when it is co-consumed with these naturally concomitant phytochemicals. The present review highlights that more research aimed at understanding the effects of these compounds is needed and, more importantly, the synergistic relationship that they may have with caffeine.

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A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans

Cited by 95 publications

References 11 publications

Caffeine's Effects on True and False Memory

Caffeine's Effects on True and False Memory

Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists

Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants

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