A dosimetric comparison of IMRT versus helical tomotherapy for brain tumors

Skórska, M.; Piotrowski, Tomasz; Kaźmierska, Joanna; Adamska, Krystyna

doi:10.1016/j.ejmp.2014.02.002

Cited by 12 publications

(13 citation statements)

References 27 publications

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“…In this study, 3DCRT was planned using a coplanar beam arrangement, whereas VMAT was planned using 3 non-coplanar arcs for each patient. There are studies that show that non-coplanar beam arrangements for 3D and VMAT can improve PTV coverage and reduce doses to OARs at the same time [17][18][19]. This difference was not factored in when analyzing the data and could help to explain the superiority seen in the VMAT plans.…”

Section: Discussionmentioning

confidence: 99%

Dosimetric comparison of peripheral NSCLC SBRT using Acuros XB and AAA calculation algorithms

et al. 2017

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There is a concern for dose calculation in highly heterogenous environments such as the thorax region. This study compares the quality of treatment plans of peripheral non-small cell lung cancer (NSCLC) stereotactic body radiation therapy (SBRT) using 2 calculation algorithms, namely, Eclipse Anisotropic Analytical Algorithm (AAA) and Acuros External Beam (AXB), for 3-dimensional conformal radiation therapy (3DCRT) and volumetric-modulated arc therapy (VMAT). Four-dimensional computed tomography (4DCT) data from 20 anonymized patients were studied using Varian Eclipse planning system, AXB, and AAA version 10.0.28. A 3DCRT plan and a VMAT plan were generated using AAA and AXB with constant plan parameters for each patient. The prescription and dose constraints were benchmarked against Radiation Therapy Oncology Group (RTOG) 0915 protocol. Planning parameters of the plan were compared statistically using Mann-Whitney U tests. Results showed that 3DCRT and VMAT plans have a lower target coverage up to 8% when calculated using AXB as compared with AAA. The conformity index (CI) for AXB plans was 4.7% lower than AAA plans, but was closer to unity, which indicated better target conformity. AXB produced plans with global maximum doses which were, on average, 2% hotter than AAA plans. Both 3DCRT and VMAT plans were able to achieve D95%. VMAT plans were shown to be more conformal (CI = 1.01) and were at least 3.2% and 1.5% lower in terms of PTV maximum and mean dose, respectively. There was no statistically significant difference for doses received by organs at risk (OARs) regardless of calculation algorithms and treatment techniques. In general, the difference in tissue modeling for AXB and AAA algorithm is responsible for the dose distribution between the AXB and the AAA algorithms. The AXB VMAT plans could be used to benefit patients receiving peripheral NSCLC SBRT.

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Section: Discussionmentioning

confidence: 99%

Dosimetric comparison of peripheral NSCLC SBRT using Acuros XB and AAA calculation algorithms

et al. 2017

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“…However, tomotherapy has been mainly used for treatment of breast cancer (341), head and neck tumors (298), prostate carcinoma (285) and sarcoma (262) at our institution. Also tumors of the brain and central nervous system (73), lymphoma (38), anal tumors (37) and gastrointestinal tumors (28) as well as skin (25), lung (22) and bone tumors (12) have been treated.…”

Section: Methodsmentioning

confidence: 99%

“…Tomotherapy was found to deliver conformal and homogeneous dose distributions with good sparing of organs at risk for treatment of brain tumors. However, non-coplanar beam arrangements that cannot be performed with tomotherapy showed to be superior with respect to reduction of dose to the eye lenses 37 .…”

mentioning

confidence: 95%

“…Mainly favorable results can be found in numerous scientific investigations 5 . They comprise prostate cancer [10][11][12][13] , head and neck tumors [14][15][16][17][18] , gastrointestinal tumors [19][20][21][22] , breast cancer 2,[23][24][25][26][27] , lung cancer [28][29][30][31][32] and intracranial lesions [33][34][35][36][37] .…”

mentioning

confidence: 99%

“…Treatment of brain tumors with tomotherapy has also been demonstrated 3,35,37 . For treatment of brain metastases with stereotactic radiotherapy 35 as well as whole brain irradiation with integrated boost 34 tomotherapy treatment revealed high dose conformity.…”

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confidence: 99%

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Helical tomotherapy: Comparison of Hi-ART and Radixact clinical patient treatments at the Technical University of Munich

Kraus

Kampfer

Wilkens

et al. 2020

Sci Rep

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The helical tomotherapy (HT) Hi-ART system was installed at our department in April 2007. In July 2018 the first Radixact system in Germany has been launched for clinical use. We present differences, advantages and disadvantages and show future perspectives in patient treatment using two Ht devices. We investigate patient characteristics, image quality, radiotherapy treatment specifications and analyze the time effort for treatments with the Hi-ART system from April 2010 until May 2017 and compare it to the data acquired in the first nine months of usage of the Radixact system. Comparing the Hi-ARt and Radixact system, the unique option of integrated MVct image acquisition has experienced distinct improvement in image quality. Time effort for irradiation treatment could be improved resulting in a mean beam on time for craniospinal axis treatment of 636.2 s for the Radixact system compared to 915.9 s for the Hi-ART system. The beneficial use of tomotherapy for complex target volumes is demonstrated by a head and neck tumor case and craniospinal axis treatment. With the Radixact system MVct image quality has been improved allowing for fast and precise interfraction dose adaptation. The improved time effort for patient treatment could increase the accessibility for clinical usage.

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Monte Carlo evaluation of the dose calculation algorithm of TomoTherapy for clinical cases in dynamic jaws mode

Sterpin

2015

Physica Medica

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A dosimetric comparison of IMRT versus helical tomotherapy for brain tumors

Cited by 12 publications

References 27 publications

Dosimetric comparison of peripheral NSCLC SBRT using Acuros XB and AAA calculation algorithms

Dosimetric comparison of peripheral NSCLC SBRT using Acuros XB and AAA calculation algorithms

Helical tomotherapy: Comparison of Hi-ART and Radixact clinical patient treatments at the Technical University of Munich

Monte Carlo evaluation of the dose calculation algorithm of TomoTherapy for clinical cases in dynamic jaws mode

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