A Door-to-Door Survey of Parkinson's Disease in a Chinese Population in Kinmen

Wang, Shuu Jiun; Fuh, Jong Ling; Teng, Evelyn L.; Liu, Chia Yih; Lin, Kon Ping; Chen, Hsi Ming; Lin, Cheng; Wang, Pei Ning; Ting, Y. C.; Wang, Hsiao Chien; Lin, Ker Neng; Chou, Pesus; Larson, Eric B.; Liu, Hsiu Chih

doi:10.1001/archneur.1996.00550010084020

Cited by 70 publications

(77 citation statements)

References 25 publications

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“…It is important to note that all marriages of Gypsies are only to other Gypsies, so they exist as genetic isolates. As Gypsies' origin is Asian [15], they would be expected to have a lower prevalence of PD, if genetic factors are responsible for the reported lower prevalence in the Asian population [4][5][6]21]. The estimated prevalence rate in this study for PD in Gypsies is comparable to that reported for the Asian population [4].…”

Section: Discussionsupporting

confidence: 54%

Prevalence of Parkinson’s Disease in Bulgarian Gypsies

Milanov¹,

Ts²,

Ke³

et al. 2000

Neuroepidemiology

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We studied the prevalence of Parkinson’s disease (PD) in Gypsies and Caucasians in Bulgaria. Cases were ascertained by examination in a clinic, a screening questionnaire and a door-to-door survey in a region of Sofia, Bulgaria. The prevalence of PD in the Gypsies was found to be 16/100,000 based on 1 case compared to 137/100,000 for Caucasians with 119 cases. It is concluded that PD is rare in Bulgarian Gypsies.

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Section: Discussionsupporting

confidence: 54%

Prevalence of Parkinson’s Disease in Bulgarian Gypsies

Milanov¹,

Ts²,

Ke³

et al. 2000

Neuroepidemiology

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“…This range is in line with our overall estimate. Studies from other parts of the world (USA, China and Argentina) have reported prevalence rates between 107 and 867 per 100,000 individuals [17,18,27,28].…”

Section: Discussionmentioning

confidence: 99%

Complete ascertainment of Parkinson disease in the Swedish Twin Registry

Wirdefeldt¹,

Gatz²,

Bakaysa³

et al. 2008

Neurobiology of Aging

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This report describes the ascertainment of Parkinson disease (PD) in all individuals aged 50 years or older (49,814 individuals) from the Swedish Twin Registry. In phase one of the study, all twins were screened for PD using telephone interviews, with a response rate of 72.7%. In phase two, twins with suspected PD were re-contacted to exclude anyone from follow-up who reported parkinsonian symptoms due to diseases other than PD. In the third phase, in-person clinical evaluations were completed for twins who were still considered PD suspects after phase two and for a sample of cotwins. During the clinical evaluations, we also collected blood samples and information about a variety of environmental exposures. Overall prevalence rate for PD was 496 per 100,000 individuals. Among the 132 PD cases identified, there were only three concordant twin pairs. In total 7.2% of PD cases reported a first degree relative with PD.

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“…Recent community surveys had often found a high percentage of new cases. In the Kinmen study [18], all subjects were examined by neurologists and the percentage of new cases was as high as 78% (18 of 23). This result is also echoed by another community study in which all were examined [1].…”

Section: Discussionmentioning

confidence: 99%

Pilot Study of Prevalence of Parkinson’s Disease in Australia

et al. 2001

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Parkinson’s disease is a common neurological disease and its prevalence increases with age. Because of an ageing population and changing environment compared to the last epidemiological study done in Australia over 30 years ago, we have conducted a door-to-door pilot survey which looked at the latest prevalence as well as putative risk factors in a random population. We used a two-phase investigation method (screening followed by detailed examination) in a random community sample of 2,820 households (with 527 individuals aged 55 and over) along with 203 residents in aged care facilities (single-phase examination for residents aged 55 and above) in the Randwick area of Sydney, New South Wales. We had a 75% participation rate in the community and a 94% in the aged care facilities. The results of the survey in this sample of 730 subjects indicated that the crude prevalence of Parkinson’s disease was between 3.6 and 4.9% (higher in the aged care facilities). The putative risk factors positively identified using chi-square method were ‘family history’ (p < 0.01) and ‘exposure to chemicals at work or in surrounding environment’ (p < 0.05). The age-adjusted prevalence rate of Parkinson’s disease revealed at least a 42.5% increase in the disease compared to 1966. We conclude that there may be an increase in the disease in Australia due to ageing and other risk factors.

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A Door-to-Door Survey of Parkinson's Disease in a Chinese Population in Kinmen

Cited by 70 publications

References 25 publications

Prevalence of Parkinson’s Disease in Bulgarian Gypsies

Prevalence of Parkinson’s Disease in Bulgarian Gypsies

Complete ascertainment of Parkinson disease in the Swedish Twin Registry

Pilot Study of Prevalence of Parkinson’s Disease in Australia

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