A multi-functional
polymer with aggregation-induced emission (AIE)-active
salicylaldehyde azine (SA) functionality and reactive oxygen species
(ROS)-responsive thioether groups is readily prepared via thiol-ene click polymerization of SA derivative diacrylate monomer,
poly(ethylene glycol) diacrylate, and 3,6-dioxa-1,8-octanedithiol.
The obtained AIE-active polymer exhibited an unexpected strong emission
in amide solvents compared to that in other common organic solvents
that was dramatically decreased by adding a trace amount of water,
suggesting that the polymer could be utilized as a water trace indicator
in amide solvents. In the backbone, the PEG segments make the polymer
well dispersed in water and the ROS-responsive thioether groups enable
this polymer as a promising ROS scavenger, with embedded SA moieties
as a fluorescent indicator for the hemolysis determination. Due to
the ability of SA moieties to complex with Cu2+, this AIE
polymer can also be utilized as a fluorescent sensor for selective
Cu2+ detection in real-world water samples. Thus, this
multi-functional polymer is anticipated to be well applied in biological
and environmental applications.