A Disposable Electrochemical Sensing Platform for Acetaminophen Based on Graphene/ZrO₂Nanocomposite Produced via a Facile, Green Synthesis Method

Method—An Investigation Into Post-Hoc Analysis Methods for Electrochemical Biosensor Data

“…Panadol and Uphamol) 19,20 and CEA present in human serum 19 respectively. The reported calibration curves for acetaminophen target 20 and CEA target 19 were used to relate the sensor responses to estimate the target concentrations respectively. For this work, the best combination of feature extraction and ML algorithms were deployed on ACE_DPV and CEA_EIS real sample datasets respectively to predict the target concentrations.…”

“…Apparatus and software.-All data collected were measured using Metrohm Autolab PGSTAT302N 19,20 and data pre-processing was performed using NOVA 1.11 from Metrohm Autolab and Scikit-learn 1.2.2. The machine models were trained using Python 3.10.12, Scikit-learn 1.2.…”

“…Different predictive models-based Support Vector Regression (SVR) and Multilayer Perceptron (MLP) were developed, and their performances were compared with linear regression as prediction baseline and calibration curve as commonly used EBs' post analysis method. The electrochemical data used in this work were from our previous reported work 19,20 and thus, the biosensor development stages will not be detailed again in this paper.…”

Prospects of nanostructure-based electrochemical sensors for drug detection: a review

“…The graphene/ZrO 2 modified screen printed carbon electrodes showed an acetaminophen detection limit of 75.5 nM, for the linear range of 10–100 μM. 129 Tamilalagan et al fabricated the (Ni/Zn)O@rGO p–n heterojunction semiconductor nanocomposite, which was used for acetaminophen detection using the DPV technique. The DPV response curve showed a linear relationship between the AP concentration and the anodic current.…”

Urbach‐Energy‐Dictated Spatial Propagation of Electrons in Thermodynamically Tuned Amorphous Zirconia Thin Films

“…[ 9–14 ] Among metal oxides used as an insulator, zirconia thin films can offer a better option in a wide variety of applications owing to their solution processability, acceptable relative permittivity (ε r ), low leakage current density ( J leak ), and high transparency in the visible region. [ 15–17 ] It should be noted that the features of the wide bandgap formation and high bandgap tunability through stoichiometric and morphological manipulations render group IV transition metal oxides such as zirconia, hafnia, and titania considered notably interesting. Therefore, exploring the behavior of electrons, the energy distribution of states, the effects of defects, and relations thereof in zirconia thin films is expected to provide a useful knowledge base for metal‐oxide‐based future electronics.…”