A Digital Logic System for the Evaluation of Instrumental Contributions to Chromatographic Band Broadening

Influence of instrumental contributions on the apparent column efficiency in high speed gas chromatography

“…It is therefore important to understand the source and magnitude of these extra column effects so that proper instrumentation may be designed for high speed analysis. The many extra column factors which contribute to peak broadening have been the subject of a number of papers (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Probably the most comprehensive treatment of this topic is that of Sternberg (10) who applied the concept of statistical moments in developing several examples of instrumental band broadening.…”

Gas chromatography

“…The applicablility of the equivalent Gaussian inlet profile for the prediction of bandwidths was evaluated by comparison of the elution profiles with those resulting from a plug inlet (236). The high precision methods of Glenn and Cram (358) for determining the instrumental contributions to HETP used an analysis of moments.…”

Moment analysis for isolation of intrinsic column efficiencies in gas chromatography

“…In elution chromatography, the breakthrough curve is given as a result of overall chromatographic effects on the solute introduced, that is, a solute undergoes not only the intrinsic column effect but also such extra-column effects as those concerned with the amount and input distribution of the solute (1-5), the diffusion and sorption in the connecting tube (6), and the performances of detector, amplifier, and recorder (7)(8)(9)(10). The mathematical expression for such a chromatographic system can be given using the convolution integral in the form W) = /"*/.…”