A difficult combination: chronic physical illness, depression, and pain

Cocksedge, Karen A; Simon, Chantal; Shankar, Rohit

doi:10.3399/bjgp14x681241

Cited by 17 publications

(6 citation statements)

References 12 publications

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“…For these 2 diagnoses, a high prevalence of depressive comorbidity has been described in epidemiological population-based studies (9,12). The significant correlation between depressive symptoms and other examined impairments and resources confirms preliminary studies (27)(28)(29)(30)(31). In this study, the prevalence of self-reported depressive symptoms in rehabilitation was examined for the first time based on a nationwide data collection.…”

Section: Discussionsupporting

confidence: 71%

Prevalence of comorbid depressive symptoms in rehabilitation: A cross-indication, nationwide observational study

Brünger

Spyra²

2016

J Rehabil Med

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Section: Discussionsupporting

confidence: 71%

Prevalence of comorbid depressive symptoms in rehabilitation: A cross-indication, nationwide observational study

Brünger

Spyra²

2016

J Rehabil Med

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“… 61 Ten studies found that differences in multimorbidity prevalence with area deprivation reduced in older age. 4 22 35 42 44 46 50 51 57 63 Inequalities across deprivation categories were greater in middle age for general multimorbidity, 4 22 35 42 44 51 57 63 in younger age groups for physical–mental multimorbidity 4 44 and mental-only multimorbidity, 44 and in older age for physical-only multimorbidity. 44 One study examining household rurality reported data showing similar associations in older vs young groups 36 (see table 3 ).…”

Section: Resultsmentioning

confidence: 99%

Household and area-level social determinants of multimorbidity: a systematic review

Ingram

Ledden

Beardon

et al. 2020

J Epidemiol Community Health

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BackgroundNo clear synthesis of evidence examining household and area-level social determinants of multimorbidity exists. This study aimed to systematically review the existing literature on associations between household and area-level social determinants of health (SDoH) and multimorbidity prevalence or incidence in the general population.MethodsSix databases (MedLine, EMBASE, PsychINFO, Web of Science, CINAHL Plus and Scopus) were searched. The search was limited to peer-reviewed studies conducted in high-income countries and published in English between 2010 and 2019. A second reviewer screened all titles with abstracts and a subset of full texts. Study quality was assessed and protocol pre-registered (CRD42019135281).Results41 studies spanning North America, Europe and Australasia were included. Household income and area-level deprivation were the most explored with fairly consistent findings. The odds of multimorbidity were up to 4.4 times higher for participants with the lowest level of income compared with the highest level. Those living in the most deprived areas had the highest prevalence or incidence of multimorbidity (pooled OR 1.42, 95% CI 1.41 to 1.42). Associations between deprivation and multimorbidity differed by age and multimorbidity type. Findings from the few studies investigating household tenure, household composition and area-level rurality were mixed and contradictory; homeownership and rurality were associated with increased and decreased multimorbidity, while living alone was found to be associated with a higher risk of multimorbidity and not associated.ConclusionImproving our understanding of broader social determinants of multimorbidity—particularly at the household level—could help inform strategies to tackle multimorbidity.

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“…However, this study excluded any patients who had died within 365 days of diagnosis. A cross sectional study of over 1.2 million adults revealed that physical and mental co-morbidities increase with age and are exacerbated by socio-economic deprivation [ 32 ]. Information regarding co-morbidities was not routinely collected and such co-morbidities could have contributed to increased global symptom burden in this study.…”

Section: Discussionmentioning

confidence: 99%

Socio-Economic Deprivation and Symptom Burden in UK Hospice Patients with Advanced Cancer—Findings from a Longitudinal Study

Lloyd‐Williams

Shiels

Dowrick

et al. 2021

Cancers

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Socio-economic deprivation is known to impact on cancer diagnosis, treatment and access to services, but little is known of the impact of socio-economic deprivation on symptom burden in patients with advanced cancer. Patients with advanced cancer attending hospice day services were recruited into a 24 week longitudinal study. An area-based index of social deprivation was collected along with depression and symptom burden at baseline, 8, 16 and 24 weeks. Of the 595 patients included, with an age range of 33–89 years and a mean age of 68 years, 67% were female, and 37% were diagnosed with cancer in the last 12 months. Twenty nine percent lived in one of the most deprived 20% of neighbourhoods. Patients living in the most socio-economically deprived areas were significantly likely to report receiving insufficient information regarding their cancer at diagnosis (p = 0.007), greater pain (p = 0.02), moderate to severe depression (p = 0.04) and higher global symptom burden (p = 0.04). This study is the first to report that patients with advanced cancer attending hospice services, living in the most deprived neighbourhoods experience significantly greater symptom burden, notably depression and pain. We recommend using patient outcome measures in order to provide targeted support and thereby reduce the increased symptom burden that socio-economically disadvantaged patients experience at the end of life.

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A difficult combination: chronic physical illness, depression, and pain

Cited by 17 publications

References 12 publications

Prevalence of comorbid depressive symptoms in rehabilitation: A cross-indication, nationwide observational study

Prevalence of comorbid depressive symptoms in rehabilitation: A cross-indication, nationwide observational study

Household and area-level social determinants of multimorbidity: a systematic review

Socio-Economic Deprivation and Symptom Burden in UK Hospice Patients with Advanced Cancer—Findings from a Longitudinal Study

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