Abstract:Purpose
The obese black and tan, brachyuric (BTBR) ob/ob mouse spontaneously develops features comparable to human diabetic nephropathy. The primary aim of the present study was to investigate if a diet containing fish proteins would attenuate or delay the development of glomerular hypertrophy (glomerulomegaly), mesangial sclerosis and albuminuria in obese BTBR ob/ob mice.
Methods
Obese BTBR.CgLepob/WiscJ male mice were fed diets containing 25% of protein … Show more
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