A DIC-like picture on plasma and ascitic fluid of cirrhotic patients

Gm, Patrassi; Sartori, Maria; Sgarabotto, Dino; Sturniolo, Giacomo; Boeri, G; Girolami, Antonio

doi:10.1007/bf01851203

Cited by 8 publications

(2 citation statements)

References 19 publications

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“…D-di-mer, a breakdown product of crosslinked fibrin, is a marker of ongoing fibrin turnover and represent an accurate marker of fibrinolytic activity (2). Previous studies have suggested the possible role of ascites in the pathogenesis of increased fibrinolysis associated with liver failure (3,4,5).…”

Section: Introductionmentioning

confidence: 99%

Association Between High D-dimer Plasma Levels and Ascites in Patients with Liver Cirrhosis

Saray

Mesihović²,

Gornjakovic³

et al. 2012

Med Arh

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Section: Introductionmentioning

confidence: 99%

Association Between High D-dimer Plasma Levels and Ascites in Patients with Liver Cirrhosis

Saray

Mesihović²,

Gornjakovic³

et al. 2012

Med Arh

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“…23 Ascites fluid reinfusion in severe cirrhosis has frequently been associated with disseminated intravascular coagulation. 24 Another intuitive finding by our method is that our model for arterial thrombosis identified affected arteries (hepatic artery, arterial occlusion); in contrast, our model for venous thromboembolism identified affected veins (portal vein thrombosis, left branch of portal vein). This finding demonstrates that our method can identify key vascular differences between these thrombotic phenotypes.…”

Section: Applying a Text-driven Approachmentioning

confidence: 80%

A Data-driven Framework for Learning and Visualizing Characteristics of Thrombotic Event Phenotypes from Clinical Texts

Davoudi

Yang

Hwang

et al. 2021

Preprint

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Automatically identifying thrombotic phenotypes based on clinical data, particularly clinical texts, can be challenging. Although many investigators have developed targeted information extraction methods for identifying thrombotic phenotypes from radiology notes, these methods can be time consuming to train, require large amounts of training data, and may miss subtle textual clues predictive of a thrombotic phenotype from notes beyond the radiology note. We developed a generalizable, data-driven framework for learning, characterizing, and visualizing clinical concepts from both radiology and discharge summaries predictive of thrombotic phenotypes.

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Concentrated ascitic fluid reinfusion after cascade filtration in tense ascites

et al. 1993

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A new method for concentrated ascitic fluid reinfusion using a double ultrafiltration device is reported as 22 procedures in 20 cirrhotic patients (6 females, 14 males; median age 55 years, range 33-69) with tense, refractory ascites. Eight of the 20 patients had elevated creatinine levels. The mean time for each procedure was 189 +/- 82 min, during which a mean of 7.7 liters (1.3-13.3) of ultrafiltered ascitic fluid was removed and 613 ml (140-1700) of concentrated ascitic fluid rich in albumin (mean: 60 g, range 14-175) was reinfused. The procedure resulted in a mean weight loss of 8.1 kg (2.2-14.0) and a mean increase of 163 ml in urine output (24 hr). A reduction in the serum creatinine level (P < 0.05) and an increase in the plasma atrial natriuretic factor level (P < 0.02) 24 hr after reinfusion, while no changes in serum albumin, plasma and urinary electrolytes, plasma renin activity, aldosterone, and antidiuretic hormone levels were noted. Although minor evidence for a disturbance in coagulation was observed, there were no episodes of clinical bleeding. Four patients (20%) had transient chills or fever. Based upon this experience, it can be concluded that reinfusion of cascade filtered and concentrated ascitic fluid is a rapid, safe, and effective treatment for patients with tense ascites; it appears to have less side effects than more traditional methods and importantly does not require administration of heterologous plasma derivatives.

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A DIC-like picture on plasma and ascitic fluid of cirrhotic patients

Cited by 8 publications

References 19 publications

Association Between High D-dimer Plasma Levels and Ascites in Patients with Liver Cirrhosis

Association Between High D-dimer Plasma Levels and Ascites in Patients with Liver Cirrhosis

A Data-driven Framework for Learning and Visualizing Characteristics of Thrombotic Event Phenotypes from Clinical Texts

Concentrated ascitic fluid reinfusion after cascade filtration in tense ascites

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