A diagnostic model for Parkinson’s disease based on circadian rhythm-related genes
Lufeng Wang,
Yiwen Bao,
Xiaofan Duan
et al.
Abstract:Background
Circadian rhythm (CR) disturbance is intricately associated with Parkinson’s disease (PD). However, the involvement of CR-related mechanisms in the pathogenesis and progression of PD remains elusive.
Methods
A total of 141 PD patients and 113 healthy participants completed CR-related clinical examinations in this study. To further investigate the CR-related mechanisms in PD, we obtained datasets (GSE7621, GSE20141, GSE20292) from the Gen… Show more
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