A diabetic odyssey: from research to guidelines. The Arnold Bloom Lecture 2002

Selective temporal lobe damage demonstrated by MRI imaging in insulin‐induced hypoglycaemia

“…Neuropathological studies in diabetic patients with fatal hypoglycaemia have widespread macroscopic abnormalities seen in cerebral cortex, hypothalamus, thalamus, cerebellum, globus pallidus and brain stem. The histology reveals features of so‐called laminar necrosis in cortical layers 2–5 in the cerebral cortex as described recently in this journal5.…”