Abstract:Purpose To identify the diagnostic value of syndecan-2 methylation in CRC patients.
Methods We searched relevant articles in eight databases. Eligible studies were analyzed. Pooled diagnostic odds ratio(DOR), positive and negative likelihood ratio(PLR and NLR), sensitivity and specificity were calculated. The summary receiver operating characteristic(SROC) curve and Fangan’s plot were drawn. Subgroup meta analyses were performed and patients with CRC at different stages or locations were compared to evaluate … Show more
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