A design implementation of the Central Process Module for an In-Beam PET in HICTD

Ke, Linghong; Yan, Junwei; Chen, J.D.; Zhang, X.L.; Wang, C.X.; Hu, Mao-Bin; Yang, Zuoqiao; Qian, Yi; She, Qianshun; Yang, Hsiharng; Zhao, H.; Pu, Tanchao; Pei, Caixia; Su, Hong; Kong, Jie

doi:10.1016/j.nima.2021.165572

Cited by 4 publications

(4 citation statements)

References 7 publications

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“…Based on previous experiences with the prototype readout electronics [9], we recently upgraded with a new DAQ system, with real-time signal processing, system calibration, and correction method. Preliminary results with the ibPET system showed that the readout electronics have a higher count rate and that the performance meets the online real-time monitoring requirement [10,11].…”

Section: Jinst 19 P04021mentioning

confidence: 99%

“…It provides approximately 15% energy resolution at 511 keV and 1.12 ns timing resolution. Then a CPM, which is able to handle up to 8 DAQU boards, with flexible and configurable energy window and coincidence time window of 350-650 keV and 1-10 ns, respectively, and also implements the time sorting and performs the coincidence finding: all the components are described in [11][12][13].…”

Section: The Ibpet Systemmentioning

confidence: 99%

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A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

Kong,

Zhou,

Wang

et al. 2024

J. Inst.

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This paper presents a heavy-ion in-beam PET, referred to as ibPET with a specifically custom designed data acquisition system, which was constructed and tested at the Heavy Ion Medical Machine (HIMM) beam-line, HICTC in Wuwei. The data acquisition system of ibPET has undergone several upgrades during the years, And its data processing capability now exceeds one million events per second per channel. To achieve optimal performance of the ibPET under existing conditions, we tested coincident events and noise equivalent count (NEC) under different time coincidence windows.The results show that the signal-to-noise ratio of the reconstructed image data reaches its peak when the time window is around 3 ns, indicating that the ibPET performance is optimal at this point. In order to determine the size of the time window, we measured the system's time resolution FWHM to be 1.63 ns, and ultimately chose a time window size of twice the time resolution FWHM, which is 3.25 ns. Meanwhile, we demonstrate the capability of our ibPET to monitor the dose range with various irradiation. The results demonstrate that the system exhibits the expected exponential decay in counting rate after irradiation, and accurately provides penetration depth positions at different energy levels.

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Section: Jinst 19 P04021mentioning

confidence: 99%

Section: The Ibpet Systemmentioning

confidence: 99%

A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

Kong,

Zhou,

Wang

et al. 2024

J. Inst.

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“…Figure 1 shows the typology of readout electronics. It comprises a DAQU and a central processing unit (CPU) [7,8]. In this system, DAQU is used to process and digitize signals from the detectors.…”

Section: Prototype Readout Electronicsmentioning

confidence: 99%

Design of multi-channel electronic prototype for ¹⁰¹Sn energy level lifetime measurement

Wang,

Yan,

et al. 2024

J. Inst.

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In this study, a 32-channel front-end data acquisition unit (DAQU) with high temporal resolution and count rate was developed at the Heavy Ion Research Facility in Lanzhou (HIRFL), China, to measure the lifetime of 101Sn on the Spectrometer for Heavy Atoms and Nuclear Structure. The DAQU data analysis module uses a field programmable gate array (FPGA) to implement and time stamp extraction through an FPGA-based tapped delay line (TDL) time-to-digital converter. The energy measurements were implemented using a trapezoidal algorithm and a sliding baseline averaging method. The DAQU was tested and calibrated using a pulse generator and cosmic rays. The results show that the system had a dead time of less than 500 ns, a dynamic range of “0” to “500” mV, and an energy resolution of better than 4.8‰ (full width at the half-maximum, FWHM). In addition, the single-channel temporal resolution under multi-channel settings surpasses 111.2 ps (FWHM), satisfying the experiment's requirements for the electronics system.

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“…The events are sorted into the chronological order for coincidence event discrimination by a novel parallel sorting algorithm in CPM. More details about the algorithm can be found in [29].…”

Section: Data Processing and Image Reconstructionmentioning

confidence: 99%

Measured and GATE predicted PET-image-based activity range verification for carbon therapy: a phantom study

et al. 2022

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In-beam PET is one of the imaging-based methods for monitoring carbon therapy by reconstruction of positron-emitters produced by incident particles. The accurate Monte Carlo simulation is necessary for range verification and therapeutic dose monitoring by means of the in-beam PET. GATE is capable of performing in-beam PET imaging but very few studies assess the accuracy of activity range measured from PET imaging with GATE simulated results. In this work, we present both experimental and GATE simulation studies of in-beam PET imaging of a phantom, which is irradiated by carbon ion beam, for range verification. The experiment data is acquired at Wuwei Heavy Ion Cancer Treatment Center in Gansu, China, with a dual-head plate PET prototype. The PET prototype consists of 2 panels, each arranged in 2 × 2 matrix. Each detector block is composed of 20 × 20 LYSO crystal array coupled with the position-sensitive photomultiplier tube (HAMAMATSU H8500). A homogeneous plastic phantom is irradiated with monoenergetic 131.05 MeV and 190.19 MeV 12C ion pencil beams. The irradiation and full response of PET prototype are simulated with GATE macros. A novel mathematical model is established, which is capable of calculating and revealing the variation of the positron activity. Our focus is on the reconstructed activity ranges obtained by the experimental measurement and GATE MC prediction combined with the positron activity distribution calculation mathematical model. Results show that the reconstructed activity distribution of experimental data and GATE MC prediction are in good agreement. The measured and simulated 1D activity peak and falling edge positions are within 1.0 mm in all cases. The 20%, 50% and 80% PET peak positions predicted by GATE are close to measurements. These results indicated that it is feasible to assess the accuracy of activity range measured from the dual-head plate PET system with the modeled GATE hadron-PET simulation.

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A design implementation of the Central Process Module for an In-Beam PET in HICTD

Cited by 4 publications

References 7 publications

A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

Design of multi-channel electronic prototype for ¹⁰¹Sn energy level lifetime measurement

Measured and GATE predicted PET-image-based activity range verification for carbon therapy: a phantom study

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A design implementation of the Central Process Module for an In-Beam PET in HICTD

Cited by 4 publications

References 7 publications

A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

A dedicated in-beam PET system with a modular dual-head for radiotherapy imaging in HIMM

Design of multi-channel electronic prototype for 101Sn energy level lifetime measurement

Measured and GATE predicted PET-image-based activity range verification for carbon therapy: a phantom study

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Design of multi-channel electronic prototype for ¹⁰¹Sn energy level lifetime measurement