A dermatologist's view of polymyositis/ dermatomyositis

Caro, Ivor

doi:10.1016/0738-081x(88)90045-4

Cited by 18 publications

(5 citation statements)

References 23 publications

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“…From a total of 24 independent reports identified in the literature (Table 2), 2–4,15–35 68 patients met our primary case definition of juvenile‐onset clinically amyopathic DM. Among the 68 patients identified, 38 (56%) were best classified as having juvenile‐onset amyopathic DM, 12 (18%) as juvenile‐onset hypomyopathic DM, and 18 (26%) as juvenile‐onset clinically amyopathic DM evolving into classical DM (Table 3).…”

Section: Resultsmentioning

confidence: 99%

A systematic review of juvenile-onset clinically amyopathic dermatomyositis

et al. 2007

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This review suggests a good prognosis for children with clinically amyopathic DM. A minority of patients with negative muscle enzymes had positive ancillary testing for myositis, and these patients rarely developed muscle weakness. Predictive factors for progression to classical DM were not identified. Symptomatic treatment of cutaneous involvement and close clinical monitoring may be an alternative to aggressive immunosuppression.

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Section: Resultsmentioning

confidence: 99%

A systematic review of juvenile-onset clinically amyopathic dermatomyositis

et al. 2007

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“…This may reflect the geographical and/or ethnic incidence of cancers [9], The cancers occurring within 1 year before or after the diagnosis of DM are the most frequent [2,3], and the clin ical signs or symptoms often lead to their discovery. These facts are also known [3,5,6,11,13], thus an extensive search including paraclinical investigations is most often unnecessary. Ovarian cancer, however, seems to repre sent an exception since it is difficult to diagnose early, and systematic pelvic examination, possibly under anesthesia, may be suggested [15,16].…”

Section: Discussionmentioning

confidence: 99%

Dermatomyositis and Malignancy

1990

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A retrospective analysis of 118 cases of dermatomyositis (DM) collected in 22 departments of dermatology over a 5-year period is presented. 34 cases (28%) were associated with a cancer that was diagnosed more than 1 year prior to (7 cases) concomitantly (22 cases) or more than 1 year after (5 cases) the occurrence of DM. There was a clear correlation between the evolution of DM and a cancer paraneoplastic evolution in 8 cases only (22%). In most of the cases, no extensive diagnostic procedures were necessary for identifying the tumors. 58% of the patients with cancer-associated DM died 20 (8–29) months after the diagnosis of DM. This multicenter study based on a short period of time confirms and extends previous observations based on retrospective single-center analyses.

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“…Hyperpigmentation is known to occur in dermatomyositis (DM) and rarely in polymyositis (PM) [11,18]. Inflammatory myopathies (DM and PM) were strong differentials in our case.…”

Section: Discussionmentioning

confidence: 62%

Young-onset Amyotrophic Lateral Sclerosis with Rare Skin Manifestation: Case Report and Literature Review

Qazi

Malik

Shafi

et al. 2020

Cureus

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Amyotrophic lateral sclerosis (ALS) is one of the most common motor neuron diseases (MND), which presents as muscle weakness, atrophy, spasticity, and, in extreme cases, may result in death due to respiratory failure. ALS has been reported with dermatological conditions such as bullous pemphigoid and decreased collagen. Hyperpigmentation usually occurs due to underlying adrenal or metabolic disorder, but no case of hyperpigmentation has been associated with MND. We report a case of a 25-year-old man who presented with signs of young-onset ALS (progressive weakness of both upper limbs) with hyperpigmentation of limbs. The patient did not have any other underlying etiology, which could have led to the development of hyperpigmentation Biopsy was negative for polymyositis and dermatomyositis. The patient was counseled about the nature of the disease and was advised regular follow-ups.

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A dermatologist's view of polymyositis/ dermatomyositis

Cited by 18 publications

References 23 publications

A systematic review of juvenile-onset clinically amyopathic dermatomyositis

A systematic review of juvenile-onset clinically amyopathic dermatomyositis

Dermatomyositis and Malignancy

Young-onset Amyotrophic Lateral Sclerosis with Rare Skin Manifestation: Case Report and Literature Review

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