A dermatologic emergency; Sweet's syndrome

Korkut, Mustafa

doi:10.1016/j.ajem.2019.06.012

Cited by 4 publications

(6 citation statements)

References 5 publications

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“…Histopathologic results reveal a dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis. In this case, the patient did not comply with the necessary criteria . In contrast, angiolymphoid hyperplasia with eosinophilia is characterized by papules or nodules with an angiomatoid aspect and that are predominantly located on the head, especially around the ears.…”

Section: Discussionmentioning

confidence: 93%

“…In this case, the patient did not comply with the necessary criteria. 7 In contrast, angiolymphoid hyperplasia with eosinophilia is characterized by papules or nodules with an angioma-toid aspect and that are predominantly located on the head, especially around the ears. The histopathologic characteristics of angiolymphoid hyperplasia with eosinophilia include abnormal vascular proliferation formed by capillaries grouped around arterial or venous vessels, with lymphocytic infiltrates with eosinophils instead of a mixed dermal infiltrate.…”

Section: Leishmaniasismentioning

confidence: 99%

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Unusual Tumor on the Earlobe

2020

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A man in his 30s presented with a 3-month history of gradual growth of a pruriginous, reddish nodule on the left ear. He had no relevant medical history. On medical examination, a reddish, smooth, superficial nodule with small dimples and a soft consistency that measured approximately 1.5 cm in diameter was seen on the left earlobe (Figure , A). It was not painful to the touch. The patient reported no history of lesions or foreign bodies at this location. A biopsy specimen was obtained for histopathologic analysis (Figure, B and C).

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Section: Discussionmentioning

confidence: 93%

Section: Leishmaniasismentioning

confidence: 99%

Unusual Tumor on the Earlobe

2020

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“…Clinically, SS is characterized by the sudden onset of multiple tender, erythematous lesions (plaques, nodules or papules), fever, neutrophilic leukocytosis, and malaise. The dermatosis papules can range from erythematous to waxy and violaceous, and can then grow to form non-pruritic, painful and tender plaques on the face, neck, upper trunk, arms, hands, and feet [ 7 , 11 , 12 , 15 , 17 ]. Presenting similarly in both children and adults, SS typically has 2 age peaks: infancy and middle age.…”

Section: Discussionmentioning

confidence: 99%

“…Improvement in clinical symptoms, laboratory markers, and imaging findings after treatment with corticosteroids further supported a diagnosis of SS. The patient met all major and minor criteria listed for classical SS [ 1 , 17 ]. From an imaging perspective, sterile abscesses should be considered in patients with a clinical diagnosis of SS and focal symptomatology.…”

Section: Discussionmentioning

confidence: 99%

Sweet syndrome with osseous and splenic involvement: A case report

Zhang

Elmaoued

Rincy

et al. 2022

Radiology Case Reports

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“…The disease can spread as a multisystemic disorder, which includes extracutaneous sites (18). It is considered a rare condition (12), however, there are several reports in humans (4,12,16,19). However, there are few reports in dogs (1,3,6,9,11).…”

Section: Introductionmentioning

confidence: 99%

Severe anemia and neutrophilic leukocytosis resembling Sweet’s syndrome in a dog

Santos,

Camargo,

Flores

et al. 2023

BJVP

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Sweet’s syndrome is a rare inflammatory condition characterized by the presence of neutrophilic infiltrate of the skin. We describe a case of severe anemia and neutrophilia with post-mortem findings resembling Sweet's syndrome in a five-years-old female Labrador Retriever with bilateral epistaxis, hematemesis, hyporexia, pale oral mucosa, and fever. Laboratory analysis evidenced severe unresponsive anemia, thrombocytopenia, and leukocytosis. Biochemistry showed hypoalbuminemia and increased ALT and SAP activities. The patient was transfused and received doxycycline and prednisone for one week without improvement. Two further blood transfusions were administered. Bone marrow analysis showed a mild erythroid hypoplasia, granulocytic hyperplasia, myeloid to erythroid ratio of 6.01:1 (reference: 0.9:1 – 1.76:1) without dysplasia, mild megakaryocytic hyperplasia, and increased iron stores. Macrophages were slightly increased in number with erythrophagocytosis, and immune-mediated anemia was considered. Immunosuppressive treatment was prescribed to reduce red blood cell destruction, but no improvement after one week was observed, and euthanasia was performed. Necroscopic findings resembled those described for the systemic form of Sweet's Syndrome. Bone marrow histopathology showed remarkably increased granulopoiesis and destruction of platelets and erythrocytes. Sweet's syndrome is frequently associated with hematologic malignancy or drug exposure. Leukemia was excluded after bone marrow analysis because no increase in blast population was seen as well as no signs of dysplasia. Previous treatment could be related to the development of Sweet's syndrome, which might be the primary event. Although rare, this syndrome should be considered in the differential diagnosis of dermatosis and leukocytosis when infectious agents are not identified.

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A dermatologic emergency; Sweet's syndrome

Cited by 4 publications

References 5 publications

Unusual Tumor on the Earlobe

Unusual Tumor on the Earlobe

Sweet syndrome with osseous and splenic involvement: A case report

Severe anemia and neutrophilic leukocytosis resembling Sweet’s syndrome in a dog

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