“…Fat acids constitute the main energy supply to the myocardium. Nevertheless, glucose plays an important role in this metabolism, once several constituents of their degradation are critical to Krebs cycle adequate functioning [27]. During ischemia, a decline of myocardial metabolism occurs, which eliminates the energy expenditure for contractile activity and focus on maintaining cellular integrity, delaying muscle contraction and relaxation through two mechanisms: initially, an increase on hydrogen ions competing for calcium ions based on troponin activation sites occurs, lentifying the actin-myosin activation and, consequently, the contraction.…”