A Decade in a Systematic Review: The Evolution and Impact of Cell Painting
Srijit Seal,
Maria-Anna Trapotsi,
Ola Spjuth
et al.
Abstract:High-content image-based assays have fueled significant discoveries in the life sciences in the past decade (2013-2023), including novel insights into disease etiology, mechanism of action, new therapeutics, and toxicology predictions. Here, we systematically review the substantial methodological advancements and applications of Cell Painting. Advancements include improvements in the Cell Painting protocol, assay adaptations for different types of perturbations and applications, and improved methodologies for … Show more
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