A curious case of convulsion

Erne, Barbara; Exner, Carolin; Frauenfelder, Thomas; Schmid, Simone; Weder, Walter

doi:10.1016/s0140-6736(10)60592-2

Cited by 12 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…; Erne et al . ). In addition, some clinical case reports also presented its ability in causing various kinds of infections such as infective endocarditis (Cunha et al .…”

Section: Introductionmentioning

confidence: 97%

“…Among the SAG species, Strep. intermedius is the most common pathogen that is often isolated from oral infectious lesions, such as periodontitis, and fatal purulent infections in internal organs, especially brain and liver abscesses (Wagner et al 2006;Erne et al 2010). In addition, some clinical case reports also presented its ability in causing various kinds of infections such as infective endocarditis (Cunha et al 2009).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm

et al. 2013

View full text Add to dashboard Cite

Aims: The aim of this study was to clarify the effects of homologous and heterologous extracellular DNAs (eDNAs) and histone-like DNA-binding protein (HLP) on Streptococcus intermedius biofilm development and rigidity. Methods and Results: Formed biofilm mass was measured with 0Á1% crystal violet staining method and observed with a scanning electron microscope. The localizations of eDNA and extracellular HLP (eHLP) in formed biofilm were detected by staining with 7-hydoxyl-9H-(1,3-dichloro-9,9-dimethylacridin-2-one) and anti-HLP antibody without fixation, respectively. DNase I treatment (200 U ml À1 ) markedly decreased biofilm formation and cell density in biofilms. Colocalization of eHLP and eDNA in biofilm was confirmed. The addition of eDNA (up to 1 lg ml À1 ) purified from Strep. intermedius, otherGram-positive bacteria, Gram-negative bacteria, or human KB cells into the Strep. intermedius culture increased the biofilm mass of all tested strains of Strep. intermedius, wild-type, HLP-downregulated strain and control strains. In contrast, the addition of eDNA (>1 lg ml À1 ) decreased the biofilm mass of all Strep. intermedius strains.Conclusions: These findings demonstrated that eDNA and eHLP play crucial roles in biofilm development and its rigidity. Significance and Impact of the Study: eDNA-and HLP-targeting strategies may be applicable to novel treatments for bacterial biofilm-related infectious diseases.

show abstract

“…; Erne et al . ). In addition, some clinical case reports also presented its ability in causing various kinds of infections such as infective endocarditis (Cunha et al .…”

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm

et al. 2013

View full text Add to dashboard Cite

show abstract

“…We reviewed the literature regarding the clinical characteristics of patients with multifocal brain abscesses caused by Streptococcus intermedius (Table 1). A total of eight patients were included, and two of them died (25%) [5][6][7][8][9][10][11][12]. Management by surgery or antibiotics depends on abscess number, size, localization, and mass effects [13].…”

Section: Discussionmentioning

confidence: 99%

Successful management of an unusual brain abscess with multiple locations: case report and review of literature

Song

Guo

2022

Preprint

View full text Add to dashboard Cite

Introduction: Intracranial abscesses at multiple locations are extremely rare and are associated with poor prognosis. High intracranial hypertension crisis and ventriculitis resulting from abscess rupture are fatal. Case report:Here, we reported a 15-year male patient with uncommon intracranial abscess involving the bilateral frontal lobe, falx cerebral, left tentorium, left occipital, and temporal subdural locations. Successful treatment was achieved after three aspirations and subsequent systemic anti-infective drug administrations. This patient recovered uneventfully, and follow-up magnetic resonance imaging revealed that the lesions had almost completely disappeared. Conclusion: This is an extremely rare case of brain abscess in multiple locations. Establishing a timely diagnosis, such as by several cultures of pus and genetic testing, is essential for the proper management of atypical cerebral abscesses.

show abstract

“…In this study, we reviewed the present case and previous literature regarding poor prognostic factors related to neurological sequelae among multiple brain abscesses caused by SAG using PubMed with the search term "multiple brain abscesses", "Streptococcus milleri", "Streptococcus intermedius" and "Streptococcus anginosus". We include all the cases with multiple brain abscesses caused by SAG from the search result [5,[10][11][12][13][14][15]. Cases with epidural, subdural abscesses, or unknown neurological sequelae were excluded from the review.…”

Section: Discussionmentioning

confidence: 99%

Focal Neurological Symptoms at Initial Presentation Could Be a Potential Risk Factor for Poor Prognosis Among Patients With Multiple Brain Abscesses by Streptococcus anginosus Group: A Case Report With Literature Review

Shibamura¹,

Miyamori²,

Tanabe³

et al. 2022

Cureus

View full text Add to dashboard Cite

Streptococcus anginosus group (SAG) is one of the most common microbes of brain abscesses. Brain abscesses caused by SAG have often delayed diagnosis since both blood and cerebrospinal fluid cultures are negative in half of the cases.A 68-year-old man developed persistent fever, headache, and myalgias for two weeks and visited our department. He was treated with oral antibiotics without laboratory work. Although examination showed no focal neurological symptoms, a careful interview revealed a history of unusual behavior for a few minutes on the previous day. Whole body contrast-enhanced computed tomography (CT) and head magnetic resonance imaging (MRI) showed two ring enhancements close to the bilateral ventricles, which were consistent with a diagnosis of the brain abscesses. An emergent surgical puncture for the larger abscess with intravenous antimicrobial therapy quickly improved his condition, and he was discharged on day 36 with no sequelae.We retrospectively reviewed works of literature on cases with multiple brain abscesses by SAG to assess potential prognostic factors for neurological sequelae. Statistical analyses of 12 cases, including 11 cases from the literature review and the current case, were performed between groups with or without poor prognosis. Among potential risk factors of age, sex, focal neurological symptoms, duration from onset to treatment, abscess formation of other organs, presence of surgical drainage, and positive for blood culture, only focal neurological symptoms at the initial presentation were significantly associated with poor prognosis (no poor prognosis, 1/4 cases vs poor prognosis group, 8/8 cases; p=0.01).Careful interviews and detailed examinations should be conducted to assess the possibility of brain abscesses among patients with fever of unknown etiology. Otherwise, a delayed diagnosis might result in poor prognoses such as death or neurological sequelae due to this disease's nature, which has few specific symptoms in the early stages.

show abstract

A curious case of convulsion

Cited by 12 publications

References 5 publications

Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm

Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm

Successful management of an unusual brain abscess with multiple locations: case report and review of literature

Focal Neurological Symptoms at Initial Presentation Could Be a Potential Risk Factor for Poor Prognosis Among Patients With Multiple Brain Abscesses by Streptococcus anginosus Group: A Case Report With Literature Review

Contact Info

Product

Resources

About